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Element
Risk
Gap
Task
Behavioral Health and Performance
Risk of Adverse Behavioral Conditions and Psychiatric Disorders
BMed1: What are the most effective methods to enhance behavioral health and prevent decrements before, during, and after spaceflight missions?
Access to Performance Data Effort
Assessing Team Performance in Autonomous Environments
Assess relationship between nutrition and behavioral health and performance
Individualized Stress Training for Long Duration Exploration Missions (NRA)
Integrated Testing of Countermeasures
Individualized Stress Training for Long Duration Exploration Missions (RR)
Research Requirements for Augmenting Sensory Stimulation (RR)
Sensory Stimulation Augmentation Tools (NRA)
Stress Inoculation Research Requirements
Survey Med Ops and Crews (evaluating current program - identify recommended changes for future missions)
Validate methods and tools on ISS and transition to medical practice
Virtual Reality (VR) Technologies for Enhancing Behavioral Health (NRA)
Ground Studies to Develop Alternative Countermeasures for Managing Stress
Countermeasure for Managing Interpersonal Conflicts in Space: A Continuation Study
Assessing the Impact of Communication Delay on Performance: An Examination of Autonomous Operations Utilizing the International Space Station
Effects of Retronasal Smelling, Variety, and Choice on Appetite and Satiety
BMed2: What are the most effective methods to predict, detect, and assess decrements in behavioral health (which may negatively affect performance) before, during, and after spaceflight missions?
Individualized Behavioral Health Monitoring Tool
Integrated Testing of Monitoring Technologies
Individualized Stress Detection System
Integrated Tools and Technologies Testing, Verification, and Validation (Flight)
Asthenia Literature Review
Multi-Modal Neurodiagnostic Tool for Stress Monitoring
Objective Detection, Evaluation and Countermeasures for In-flight Depression
Objective Monitoring of Crew Neurobehavioral Functions in Mars 520-Day Simulation
Objective Monitoring of Crew Neurobehavioral Functions (105-day Russian Chamber Study)
Optical Computer Recognition (OCR) of Stress, Affect and
Fatigue during Performance in Space Flight - Phase II
Optical Computer Recognition of Stress, Affect and Fatigue During Performance in Spaceflight
Neurobehavioral Conditions List for Exploration Missions
Voice Content Analysis Techwatch
Optical Computer Recognition of Performance Under Stress
BHP Dashboard: Flight Validation and Risk Characterization
BHP Dashboard: Ground Validation and Risk Characterization
BMed3: What aspects, if any, of cognitive performance change in-flight? If there are changes, do they persist post mission? If so, for how long?
Antarctic Long Duration Neurostructural Change (NRA)
Detection & Prevention of Neurobehavioral Vulnerability to Space Radiation
Evidence Review: Cognition in Long Duration Missions in Isolated, Confined and Extreme Environments
Integrated Workshop (Sensorimotor/SHFE/Sleep) Decision Point
NSCOR (TBD)
Speech monitoring of cognitive deficits and stress
Detection and Prevention of Neurobehavioral Vulnerability to Space Radiation
Mitigating Neurobehavioral Vulnerabilities to Space Radiation (Postdoctoral Fellowship)
Spaceflight Effects on Neurocognitive Performance: Extent, Longevity, and Neural Bases
BMed4: What are the most effective methods for detecting and assessing cognitive performance during exploration missions?
CogGauge: A Cognitive Assessment Tool (Phase II)
CogGauge: A Cognitive Assessment Tool (Phase III)
CogGauge Enhancement
Team Cohesion and Cognition (fMRI) Literature Review
Individualized Real-Time Neurocognitive Assessment Toolkit for Space Flight Fatigue
BMed5: What individual characteristics predict successful adaptation and performance in an isolated, confined and extreme environment, especially for long duration missions?
South Pole Station: An Analogue for Human Performance During Long Duration Missions to Isolated and Confined Environments
Evidence Review on Identification of Psychosocial Characteristics in ICE Environments
Investigation into underlying mechanisms re: individual differences in adaptation (NRA)
Investigation into underlying mechanisms re: individual differences in adaptation (RR)
Meta-Analysis of the effects of ICE environments
Synthesis of all Meta-Analyses related to the effects of ICE environments on Subjective Well-Being
Growth and Resiliency Review
The Prediction of the Onset of Anxiety Disorders
White Paper on the Onset of Depression
Markers of Susceptibility to Neurobehavioral Decrements in Space Flight
BMed6: What are the most effective methods for treating the individual to remedy behavioral health problems during spaceflight missions (including behavioral health meds)?
A Multi-Media, Computer-Based, Self-Directed, Autonomous, Stress and Anxiety-Management Countermeasure
Behavioral Issues Associated with Long Duration Space Missions: Review of Astronaut Journals
Behavioral Issues Associated with Long Duration Space Missions: Review of Astronaut Journals - Extension
Interactive Cognitive Behavioral Therapy
BMed/Team Workshop
Investigate chronic, psychological stress role in reactivation of viruses; identify countermeasures
Investigate medical treatment (asynchronous telemedicine in analog environment)
Self-Guided Depression Treatment on Long-Duration Spaceflights
Self-Help Depression Tool- COTS Mod
Self-Help Stress/Anxiety/Affect-Virtual Therapist Ground Analog Study
Techwatch re: Asynchronous Behavioral Health Therapy
Test SSRIs as countermeasure for neurostructural change and decline
Pharmacology Database
BHP Medications – Spaceflight Concerns
BMed7: What are the most effective methods for modifying the environment to prevent and remedy behavioral health problems during spaceflight missions?
Environmental Factors Evidence Review
Virtual Reality (VR) Technologies for Enhancing Behavioral Health
Virtual Reality (VR) Technologies for Enhancing Behavioral Health (NRA)
Ground Studies to Develop Alternative Countermeasures for Managing Stress
Literature review - the physical environment, BHP outcomes, and habitability requirements
BMed8: How do family, friends, and colleagues affect astronauts’ behavioral health and performance before, during, and after spaceflight?
Determine best methods and tools to maintain contact with astronaut social support network during pre-mission training (Pre-flight)
Determine best protocols for reintegration for their personal support network after spaceflight missions. (Post-flight)
Evaluate most effective modes of communication between LD crewmembers and their family, friends, and colleagues in providing emotional support during spaceflight (e.g., email, voicemail, asynchronous video message) (In-flight)
Identify current behavioral health support operations and changes that may be needed to continue to support the astronauts and their families, friends, and colleagues during long duration missions
Lit review of the biological basis of emotional support
Risk of Performance Decrements Due to Inadequate Cooperation, Coordination, Communication, and Psychosocial Adaptation within a Team
Team Gap 1 (Formerly Team1): We need to understand the key threats, indicators, and life cycle of the team for autonomous, long duration and/or distance exploration missions.
Risk Assessment – Task Performance, Teamwork, and Psychosocial Performance
Access to Performance Data Effort
Examination of Cultural Interactions Using Archival Data Footage on ISS
Job Analysis
Long Duration Antartica Study - Teams in ICE
Long Duration ISS Space Flight Study
NSCOR: Long Duration Analog Studies (Russian Chamber)
Psychosocial Factors Model Development
Review of Team Function Benchmarking Studies (Duration/Distance)
Literature Review and Operational Assessment of Psychosocial Strategies related to BHP
BMed/Team Workshop
Assessing the Impact of Communication Delay on Performance: An Examination of Autonomous Operations Utilizing the International Space Station
Investigating the Influence of Personality on Performance Within the Astronaut Population
Psychosocial Performance Factors in Space Dwelling Groups (PI Roma)
Team Gap 2 (Formerly Team 2): We need to identify a set of validated measures, based on the key indicators of team function, to effectively monitor and measure team health and performance fluctuations during autonomous, long duration and/or distance exploration missions.
Automated Behavior and Cohesion Assessment Tools
Behavior Tracking Software Enhancement and Integration of a Feedback Module
Literature Review and Operational Assessment of Monitoring Tools and Technologies related to BHP
Monitoring Tools TEAM Mental Model Requirements
Analog Validation Study of Team Measures
Field test of a simple, rapid, and objective behavioral assay of group cohesion in an antarctic space analog environment
Developing, Maintaining, and Restoring Team Cohesion
Monitoring and Regulating Teamwork
Development of an Objective Behavioral Assay of Cohesion to Enhance Composition, Task Performance, and Psychosocial Adaptation in Long-Term Work Groups
AD ASTRA: Automated Detection of Attitudes and States through Transaction Recordings Analysis
Team Gap 3 (Formerly Team 3): We need to identify a set of countermeasures to support team function for all phases of autonomous, long duration and/or distance exploration missions.
Spaceflight CM Validation Studies
Countermeasure for Managing Interpersonal Conflicts in Space: A Continuation Study
Just-in-Time, Cross Training Countermeasures
Literature Review and Operational Assessment of Countermeasures Related to BHP
Support/Adaptation Countermeasures
Crew Scheduling Tools
Factors Contributing to Food Acceptability and Consumption, Mood, and Stress on Long-term Space Missions
Literature Review and Operational Assessment of Communication Strategies related to BHP
Assessing the Impact of Communication Delay on Performance: An Examination of Autonomous Operations Utilizing the International Space Station
A Scheduling and Planning Tool in NEEMO 14 – A Simulated Space Environment
Protocols for Asynchronous Communication in Space Operations: Communication Analysis
Team Gap 4 (Formerly Team 4): We need to identify psychological measures that can be used to select individuals most likely to maintain team function for autonomous, long duration and/or distance exploration missions.
Selection Studies Retrospective
Virtual Reality (VR) Technologies for Enhancing Behavioral Health
Team Gap 5 (Formerly Team 5): We need to identify validated team training methods that can be used to maintain team function in autonomous, long duration and/or distance exploration missions.
Training Needs Analysis
Simulation Run to Test Training
Analog Training Studies
Optimizing Crew Performance in Long Duration Space Exploration: Best Practices for Team Training and Cohesion Measurement
Communications Training Review Requirements
Literature Review and Operational Assessment of Training Strategies related to BHP
Training and Culture
Virtual Reality Pre-Mission Training Countermeasures
Enhancing team performance for exploration missions (NASA PI)
Team Gap 6 (Formerly Team 6): We need to identify the best methods to support and enable multiple distributed teams to maintain team function in autonomous, long duration and/or distance exploration missions.
Assessing Team Performance in Autonomous Environments
Autonomy Literature Review Requirements
Crew Interactions and Autonomy During Long-Duration Isolation and Confinement (105-Day Russian Chamber Study)
Autonomy Workshop
Effects of high vs. Low Autonomy on Crewmember Performance in analogues
Team Gap 8 (Formerly Team 4): We need to identify psychological and psychosocial factors, measures, and combinations thereof that can be used to compose highly effective crews for autonomous, long duration and/or distance exploration missions.
Leader-Followership Team Composition
Specialized Roles Team Members
Composing and Developing Resilient, Adaptive, and Self-Sustaining Teams for Long Duration Space Exploration
Field test of a simple, rapid, and objective behavioral assay of group cohesion in an antarctic space analog environment
Team Gap 9: We need to identify spaceflight acceptable thresholds (or ranges) of team function, based on key indicators, for autonomous, long duration and/or distance exploration missions.
Risk of Performance Errors Due to Fatigue Resulting from Sleep Loss, Circadian Desynchronization, Extended Wakefulness, and Work Overload
Sleep1: What are the most effective tools to detect and assess performance decrements due to fatigue resulting from sleep loss, circadian desynchronization, extended wakefulness, and work overload?
Integrated Cognitive Assessment: Combining Measurement, System, and Mission
Psychomotor Vigilance Test (PVT) on ISS
Psychomotor Vigilance Test (PVT) Transition to Operations
Validation of Assessment Tests and Countermeasures for Detecting and Mitigating Changes in Cognitive Function During Robotics Operations
Individualized Real-Time Neurocognitive Assessment Toolkit for Space Flight Fatigue
Android App Incorporating the PVT to deliver individualized Fatigue Risk Management in Commercial Trucking
Development of a User Interface for the PVT SelfTest (PST)
Sleep2: How is performance in space flight affected by fatigue due to sleep loss, circadian desynchronization, extended wakefulness and work overload?
Cognitive Performance and Stress in a Simulated Space Environment
Assess PVT Data: Ground/Flight
Characterize Sleep Structure on ISS
Sleep3: Does sleep loss continue on long duration spaceflight or is there adaptation? What is the nature of circadian desynchronization, extended wakefulness and work overload over long duration missions?
Sleep-Wake Actigraphy and Light Exposure During Spaceflight
Techwatch for Sleep Monitoring Technologies for Long Duration Spaceflight
Transition Actiwatch Protocol to Medical Operations
Characterize Workload on ISS
Decision point: Tools for measuring sleep structure and duration in space
Sleep4: How can individual astronauts’ vulnerabilities to sleep loss and circadian rhythm disruption best be determined?
Assess Relevant Investigations / Potential Collaborations Across Other Agencies
Evidence Review on Biomarkers of Individual Vulnerabilities to Sleep Loss and Circadian Desynchronization
Biomarkers to Assess Individual Vulnerabilities and Resiliences to Sleep Loss and Circadian Desynchronization
Mathematical Modeling of Circadian/Performance Countermeasures
Markers of Susceptibility to Neurobehavioral Decrements in Space Flight
Sleep5: How can light be used to prevent and mitigate health, performance, and safety problems due to circadian, neuroendocrine, and neurobehavioral disruption, for flight, surface and ground crews?
SSLM Flight Study
Ultra-Short Light Pulses as Efficient Countermeasures for Circadian Misalignment and Objective Performance and Subjective Alertness Decrements
The ISS Dynamic Lighting Schedule: An in-flight lighting countermeasure to facilitate circadian adaptation, improve sleep and enhance alertness and performance on the International Space Station
Lighting Workshop
Feasibility Pilot Study on Acute Biological and Behavioral Responses to the Solid State Lighting Modules for the International Space Station
Blue Light for Enhancing Alertness in Space Missions
Characteristics of Light Exposure Necessary for Development of Optimal Countermeasures to Facilitate Circadian Adaptation and Enhance Alertness and Cognitive Performance in Space
Evaluation of Photic Countermeasures for Circadian Entrainment of Neurobehavioral Performance and Sleep-Wake Regulation Before and During Spaceflight
Optimizing Light for Long Duration Space Exploration
Replacement Lighting for Research and Training
Operational Evaluation of Photic Countermeasure to Improve Alertness, Performance, and Mood during Nightshift Work on a 105-Day Study (105-day Russian Chamber Study)
A Model of Circadian Disruption in the Space Environment
Evidence Review: long term safety effects of low spectrum light exposure
Sleep6: How can individual crew members most effectively and safely use sleep and alertness medications prior to and during spaceflight?
Develop and Implement Operational Ground Testing Protocols to Individualize Astronaut Sleep Medication Efficacy and Individual Effects (pilot study)
Operational Ground Testing Protocols to Individualize Astronaut Sleep Medication Efficacy and Individual Effects
Pharmacology Database
Sleep7: Does sleep loss, circadian desynchronization, work overload and extended wakefulness as it is experienced on long duration missions, affect well-being, crew interaction and performance? If so, how?
The role of sleep and circadian phase on crew safety, performance and psychological health during long-term analog space missions
Sleep8: How can predictions of the effects of chronic work-rest schedules on performance be used to prevent work overload and mitigate risk?
Countermeasures for Performance Deficits from Sleep Loss and Workload in Space Flight
Designing Individual Countermeasures to Reduce Sleep Disruption and Improve Performance and Alertness in Space
Individualized Fatigue Meter for Space Exploration (SBIR Phase II)
Physiologically-Based Modeling of Sleep-Wake Scheduling and the Effects of Pharmaceuticals (NSBRI Postdoctoral Fellowship)
Mathematical Modeling of Circadian/Performance Countermeasures
Sleep9: What are the countermeasures needed to recover from chronic partial sleep loss, work overload, and/or slam sleep shifting, and that permit recycle back into the same sleep-restricted schedules?
Countermeasures to Neurobehavioral Deficits from Cumulative Sleep Deprivation During Space Flight: Dose-Response Effects of Recovery Sleep Opportunities
Assess Sleep Recovery Research Findings from Other Agencies
Sleep10: What flight rules and requirements improve sleep, circadian desynchronization, fatigue and work overload, to reduce performance errors?
A Comprehensive Fatigue Management Program and an Evaluation of a Photic Countermeasure for Mission Controllers
Phoenix Scout Lander: Countermeasures Testbed for Spaceflight Ground Controllers
Survey of On-Orbit Sleep Quality (Sleep Quality Questionnaire)
Exploration Medical Capability
Risk of Unacceptable Health and Mission Outcomes Due to Limitations of In-flight Medical Capabilities
ExMC 1.01: Inadequate information on preflight medical screening capabilities for exploration class missions
Cardiovascular Imaging and Strategies to Mitigate the Risk for Cardiac Events in Astronauts During Prolonged Spaceflight
Comparison of open vs. closed access wiki models for the Human Research Wiki
Technology Watch
Human Research Wiki
ExMC 1.02: Inadequate information on genetic screening technology (MERGED WITH ExMC 1.01)
ExMC 1.03: Inadequate information on the individual susceptibility to hypobaric environments (e.g. 7.2 psi lunar habitat) (CLOSED)
Data Mining/Identification of characteristics associated with susceptibility to hypobaric environments
ExMC 2.01: We do not know the quantified mission and crew health consequences due to medical events for exploration – class missions.
Integrated Medical Model (IMM)
Integrated Medical Model - Chest Injury Module
Integrated Medical Model - Head Injury Module
Integrated Medical Model - Abdominal Injury Module
Integrated Medical Model - Bayesian Analysis
Integrated Medical Model - Neck Injury Module
Probabilistic Analysis of Renal Stones in US Astronauts
Comparison of open vs. closed access wiki models for the Human Research Wiki
Data Request for Sleep-Deprivation Medical Intervention Forecasting (SDMIF)
Human Research Wiki
ExMC 2.02: We do not know the quantified crew health and mission impacts of including a physician crew medical officer on exploration missions
Quantify impacts of including various levels of clinical training within the crew
Comparison of open vs. closed access wiki models for the Human Research Wiki
Human Research Wiki
Technology Watch
Long-Duration Cross-Training Feasibility and Methods (Pre-flight and Onboard)
ExMC Support of Medical Scenarios for the Autonomous Mission Operation (AMO) Test
ExMC 3.01: We do not know the optimal training methods for in-flight medical conditions identified on the Space Medicine Exploration Medical Condition List taking into account the Crew Medical Officer’s clinical background
Data mining of post-flight medical crew debriefs for information on crewmember medical training effectiveness
Evaluation of Task-Skill-Knowledge JIT techniques for medical and other emergency events
Medical Proficiency Training
Tools and methods to ensure training retention for long-duration missions
Comparison of open vs. closed access wiki models for the Human Research Wiki
Human Research Wiki
Technology Watch
ExMC Support of Medical Scenarios for the Autonomous Mission Operation (AMO) Test
ExMC 3.02: Lack of knowledge about the current state of the art in telementoring/telemedicine as a tool for assisting crewmembers to diagnose and treat medical conditions that occur in space flight (CLOSED)
Data mining for telementoring studies and practices
Telemedicine Workshop
Comparison of open vs. closed access wiki models for the Human Research Wiki
ExMC 3.03: Inadequate information on capabilities for in-flight screening and diagnosis of conditions on the Space Medicine Exploration Medical Condition List
Determine requirements for in-flight periodic health status exams based on Space Medicine Exploration Medical Condition List
Comparison of open vs. closed access wiki models for the Human Research Wiki
Human Research Wiki
Technology Watch
ExMC 4.01: Lack of guided medical procedure system that integrates with medical hardware
Assisted Medical Procedures (AMP)
(formerly: Advanced Integrated Clinical System - Guided Medical Procedure System)
Integration of iRevive with the Lightweight Trauma Module
Comparison of open vs. closed access wiki models for the Human Research Wiki
Human Research Wiki
Technology Watch
Information Integration for Electronic Procedures
Advanced concepts for information integration and presentation
ExMC Support of Medical Scenarios for the Autonomous Mission Operation (AMO) Test
ExMC 4.02: Limited non-invasive diagnostic imaging capability and techniques to diagnose conditions on the Space Medicine Exploration Medical Condition List
Combined Scanning Confocal Ultrasound Diagnostic and Treatment System for Bone Quality Assessment and Fracture Healing
Non-Ultrasound Imaging Device
Intuitive Ultrasound Catalog for Autonomous Medical Care
Flexible Ultrasound System
Ultrasound Fracture Diagnosis in Space
Validation of On-Orbit Methodology for the Assessment of Cardiac Function and Changes in the Circulating Volume Using Ultrasound and Braslet-M Occlusion Cuffs, SDTO 17011 U/R
Comparison of open vs. closed access wiki models for the Human Research Wiki
Wideband Single Crystal Transducer for Bone Characterization
Human Research Wiki
Technology Watch
Multi-Use Near-Infrared Spectroscopy System for Spaceflight Health Applications
ExMC 4.03: Limited capability to treat back/neck pain and injuries in the space flight environment
Data Mining for Intervertebral Disk Damage
Risk of Intervertebral Disc Damage After Prolonged Spaceflight
Sonographic Astronaut Vertebral Examination
Comparison of open vs. closed access wiki models for the Human Research Wiki
Understand back/neck pain etiology
Human Research Wiki
Technology Watch
ExMC 4.04: We do not know what technologies can be used to provide supplemental oxygen to ill crewmembers from onset of illness through landing and recovery and also minimize the local and cabin oxygen buildup to avoid increasing the risk of fire.
Development of Pressure Swing Adsorption Technology for Spaceflight Medical Oxygen Concentrators
Evaluation of Oxygen Concentrators at Altitude
Medical Oxygen Fire Safety
Portable Cathode-Air-Vapor-Feed Electrochemical Medical Oxygen Concentrator
ISS Flight Demonstration of Oxygen Concentrator
Lightweight Trauma Module
Comparison of open vs. closed access wiki models for the Human Research Wiki
Human Research Wiki
Technology Watch
ExMC 4.05: Lack of minimally invasive in-flight laboratory capabilities with limited consumables required for diagnosing identified Exploration Medical Conditions
In-flight Blood Analysis Technology for Astronaut Health Monitoring
Nanoscale Test Strips for Multiplexed Blood Analysis
Reusable Handheld Electrolytes and Lab Technology for Humans
Comparison of open vs. closed access wiki models for the Human Research Wiki
Lander/Outpost Inflight Lab Analysis-ARC
Human Research Wiki
Technology Watch
ExMC 4.06: Limited capability to stabilize and treat bone fractures
Combined Scanning Confocal Ultrasound Diagnostic and Treatment System for Bone Quality Assessment and Fracture Healing
Comparison of open vs. closed access wiki models for the Human Research Wiki
Human Research Wiki
Technology Watch
Methods/Technologies for treatment of bone fracture
ExMC 4.07: Limited wound care capability to improve healing following wound closure
Data Sharing Activity to Gather Evidence for Impaired Healing Risk
Comparison of open vs. closed access wiki models for the Human Research Wiki
Human Research Wiki
Technology Watch
ExMC 4.08: Limited capability to treat muscle, ligament, and tendon injuries
Development of methods/technologies for treating MLT injuries
Comparison of open vs. closed access wiki models for the Human Research Wiki
Human Research Wiki
Technology Watch
ExMC 4.09: Lack of medical suction and fluid containment capability for chest tube and airway management in partial gravity and microgravity environments
Development of Methods/Technologies for Medical Suction
Comparison of open vs. closed access wiki models for the Human Research Wiki
Human Research Wiki
Technology Watch
ExMC 4.10: Lack of rapid vascular access capability for space flight (CLOSED)
Intraosseous (IO) Access Device Demonstration
ExMC 4.11: Limited dental care capabilities
Exploration Dental Capabilities for EMSD
CDDF/Innovative Treatments of Dental Emergencies for Lunar and Exploration Missions
Development of Methods/Technologies for Dental Conditions
Comparison of open vs. closed access wiki models for the Human Research Wiki
Human Research Wiki
Technology Watch
ExMC 4.12: Lack of in situ intravenous (IV) fluid generation and resource optimization capability
Fluid Resuscitation – Closed Loop
Intravenous Fluid GENeration for Exploration Missions
IVGEN Gap Analysis
Comparison of open vs. closed access wiki models for the Human Research Wiki
Human Research Wiki
Technology Watch
ExMC 4.13: Limited capability to diagnose and treat a renal stone during an exploration mission
Smart Therapeutic Ultrasound Device for Mission-Critical Medical Care
Comparison of open vs. closed access wiki models for the Human Research Wiki
Human Research Wiki
Technology Watch
ExMC Support of Medical Scenarios for the Autonomous Mission Operation (AMO) Test
ExMC 4.14: Lack of efficient medical consumable inventory tracking system that provides data on overall usage and usage rate and integrates securely with vehicle inventory management system
Medical Consumables Tracking- GRC
Comparison of open vs. closed access wiki models for the Human Research Wiki
Human Research Wiki
Technology Watch
ExMC 4.15: Lack of medication usage tracking system that includes automatic time stamping and crew identification
Medical Consumables Tracking- GRC
Comparison of open vs. closed access wiki models for the Human Research Wiki
Human Research Wiki
Technology Watch
ExMC 4.16: Lack of technique or procedure to draw injectable medication into a syringe without bubble formation or bubble removal prior to medication delivery (CLOSED)
Air/Fluid Separation in a Syringe in a Microgravity Environment
Injectible medication study for ISS Medical Kit Redesign
ExMC 4.17: Lack of adequate protection for medications to preserve stability and shelf-life in exploration class missions
Development of methods/technologies for protecting medications in spaceflight
Comparison of open vs. closed access wiki models for the Human Research Wiki
Human Research Wiki
Technology Watch
ExMC 4.18: Limited biomedical monitoring capability for exploration extravehicular activity suits
Biomedical Sensors (EVA) ARC
Noninvasive Biosensor Algorithms for Continuous Metabolic Rate Determination
Comparison of open vs. closed access wiki models for the Human Research Wiki
Human Research Wiki
Technology Watch
ExMC 4.19: Limited biomedical sensing capabilities for intravehicular activities (such as performing periodic clinical status evaluations and contingency medical monitoring)
Development of methods/technologies for intravehicular activity biomedical monitoring
Lightweight, Wearable Metal Rubber-Textile Sensor for In-Situ Lunar Autonomous Health Monitoring
Lunar Health Monitor: A Wearable System to Monitor Astronaut Health Status
Wearable Health Monitoring Systems
Comparison of open vs. closed access wiki models for the Human Research Wiki
Biomedical Sensors (IVA)
Biosensor Integration
Biomedical Sensors
Human Research Wiki
Technology Watch
Biosensors for EMSD
ExMC 4.20: Lack of a system to manage medical data collected from the patient in space flight that integrates with ground operations (MERGED WITH ExMC 5.01)
ExMC 4.21: Limited eye wash capability to treat chemical eye exposure in partial gravity and microgravity environments
Development of Methods/Technologies for Eye Wash Capability
Comparison of open vs. closed access wiki models for the Human Research Wiki
Human Research Wiki
Technology Watch
ExMC 4.22: Limited capability to diagnose and treat radiation sickness
Development of methods/technologies for treating radiation sickness
Comparison of open vs. closed access wiki models for the Human Research Wiki
Human Research Wiki
Technology Watch
ExMC 4.23: Limited capability to auscultate internal sounds of the body in a noisy, space flight environment
Development of Methods/Technologies to Auscultate and Capture Body Sounds in a Noisy Environment
Comparison of open vs. closed access wiki models for the Human Research Wiki
Human Research Wiki
Technology Watch
ExMC 4.24: Lack of knowledge regarding the treatment of conditions on the Space Medicine Exploration Medical Condition List in remote, resource poor environments
Research Treatment of Relevant Medical Conditions in Remote, Resource Poor Environments
Comparison of open vs. closed access wiki models for the Human Research Wiki
Human Research Wiki
Technology Watch
ExMC Support of Medical Scenarios for the Autonomous Mission Operation (AMO) Test
ExMC 4.25: Lack of capability to deliver medication to a crewmember in a pressurized suit
Spaceflight Injectable Delivery System
Comparison of open vs. closed access wiki models for the Human Research Wiki
Human Research Wiki
Technology Watch
ExMC 4.26: Limited capability to diagnose and treat pulmonary or systemic disease due to non-terrestrial dust exposure
Development of methods/technologies to monitor and treat disease caused by non-terrestrial dust exposure
LADTAG Lunar Dust Health Standard
Review and Assess State of Knowledge Regarding the Acute or Chronic Cardiovascular Toxicity of Mineral Dusts
Clearance of Particles Depositing in the Human Lung in Low-Gravity
Comparison of open vs. closed access wiki models for the Human Research Wiki
Human Research Wiki
Technology Watch
ExMC 4.27: Limited capability to sterilize medical equipment in space flight
Development of methods/technologies to sterilize medical equipment in spaceflight
Comparison of open vs. closed access wiki models for the Human Research Wiki
Human Research Wiki
Technology Watch
ExMC 5.01: Lack of end-to-end medical data management infrastructure for exploration class missions
Exploration Medical System Demonstration on ISS
Middleware for EMSD
Electronic Medical Records
Biosensors for EMSD
Exploration Dental Capabilities for EMSD
Mission Medical Information System
Distributed System for Spaceflight Biomedical Support
Comparison of open vs. closed access wiki models for the Human Research Wiki
Mission Extended Medical Enterprise
Human Research Wiki
Technology Watch
Exploration Medical System Demonstration (EMSD) Baseline Capability Evaluation using the HDU
EMSD Ground Demonstration
EMSD-Flight Demonstration
Human Health Countermeasures
Risk Factor of Inadequate Nutrition
N2: What is the adequate dose range of vitamin D supplementation?
Efficacy of Vitamin D Supplementation in an Antarctic Ground Analog of Space Flight
Nutritional Status Assessment: SMO-016E
Vitamin D Supplement Evaluation of Dosing Requirements
Vitamin D Supplementation in an Antarctic Ground Analog of Space Flight: Study of Supplementation Protocol and Relationship to Immune System Function
Evaluation of the effect of short duration spaceflight on hepatic nutrition, oxidative damage, and colon microflora
Concordia: D, Immune and Metabolism
Evaluate Energy Expenditure During Long-duration (>3mo) Missions.
N3: How do nutritional status/nutrition requirements change during spaceflight?
Nutritional Status Assessment: SMO-016E
Evaluate Energy Expenditure During Long-duration (>3mo) Missions.
Evaluation of the effect of short duration spaceflight on hepatic nutrition, oxidative damage, and colon microflora
Issues Related to Systemic Inflammatory Response
Biochemistry Profile Surveillance
N4: Do countermeasures impact nutrition?
Nutrition/Pharm Interactions
N6: What impact does the spaceflight environment have on oxidative damage?
(NEEMO Nut ROI) Oxidative Damage During a 12-day Saturation Dive
Characterization of Oxidative Damage During a Saturation Dive
Nutritional Status Assessment: SMO-016E
Oxidative Damage Study
Evaluation of the combined effects of gamma radiation and high dietary iron on oxidative damage and antioxidant status in rats
Evaluation of the effect of short duration spaceflight on hepatic nutrition, oxidative damage, and colon microflora
Effects of high dietary heme iron and radiation on cardiovascular function
Biochemistry Profile Surveillance
N9: What are the interactions of exercise and nutrition in altered weight bearing environments that mitigate muscle loss?
Exercise Plus Nutritional Supplement Studies
Loading-Independent Factors that Contribute to Spaceflight-Induced Muscle Loss
Evaluate n-3 Fatty Acids as a Countermeasure for Bone Loss
N14: What integrated nutritional, exercise and/or pharmaceutical countermeasures can be used to mitigate bone loss?
Dietary Intake Can Predict and Protect Against Changes in Bone Metabolism During Space Flight and Recovery (Pro-K)
Nutritional Status Assessment: SMO-016E
Exercise Plus Nutritional Supplement Studies
Integrated Resistance and Aerobic Training Study
Epidemiologic Analyses of Risk Factors for Bone Loss and Recovery Related to Long Duration Space Flight
Feasibility Study: QCT Modality for Risk Surveillance of Bone - Effects of In-flight Countermeasures on Sub-regions of the Hip Bone
Evaluate n-3 Fatty Acids as a Countermeasure for Bone Loss
Evaluation of the effect of short duration spaceflight on hepatic nutrition, oxidative damage, and colon microflora
Nutritional countermeasures to ameliorate losses in muscle mass and function
Biochemistry Profile Surveillance
N15: Can nutrition/nutrients mitigate O2/radiation risks?
(NEEMO Nut ROI) Oxidative Damage During a 12-day Saturation Dive
Characterization of Oxidative Damage During a Saturation Dive
Nutritional Status Assessment: SMO-016E
Oxidative Damage Study
Investigation to Determine Countermeasures to Lower Body Iron Stores to Mitigate O2/Radiation Risks
Evaluation of the combined effects of gamma radiation and high dietary iron on oxidative damage and antioxidant status in rats
Evaluation of the effect of short duration spaceflight on hepatic nutrition, oxidative damage, and colon microflora
Biochemistry Profile Surveillance
Novel Double-Hit Mouse Model to Investigate Oxidative Damage from Radiation/ Hyperoxia Related to Space Exploration - Evaluation of Dietary Flaxseed as Countermeasure
M23: Do factors in addition to unloading contribute to muscle atrophy during space flight (e.g. radiation, inflammation, hydration, redox balance, energy balance)?
Gender Effects on Muscle
Role of Energy Balance in Maintaining Muscle and Bone
Loading-Independent Factors that Contribute to Spaceflight-Induced Muscle Loss
Redox Modulation of Skeletal Muscle Function in Microgravity
N5: Can a single test monitor net bone calcium changes?
Rapid measurements of bone loss using tracer-less calcium isotope analysis of blood and urine
Anbar Follow-On Studies
Risk of Bone Fracture
Fracture 1 (B31): We don't understand how the space flight environment affects bone fracture healing in-flight.
Fracture Healing in Haversian Bone under Conditions of Simulated Microgravity
Extent, Causes, and Countermeasures of Impaired Fracture Healing in Hypogravity
Combined Scanning Confocal Ultrasound Diagnostic and Treatment System for Bone Quality Assessment and Fracture Healing
Astronaut Bone Medical Standards Derived from Finite Element [FE] Modeling of QCT Scans from Populations Studies
A Scanning Confocal Acoustic Diagnostic System for Non-Invasively Assessing Bone Quality
Ultrasound Add-On to Puttlitz
Fracture 2 (B30): We need to characterize the loads applied to bone for standard in-mission activities.
Ultrasound Add-On to Puttlitz
Digital Astronaut: Bone Physiology Model
Fracture 3 (B30): We need a validated method to estimate the the risk of fracture by evaluating the ratio of applied loads to bone fracture loads for expected mechanically-loaded activities during a mission.
Feasibility Study: QCT Modality for Risk Surveillance of Bone - Effects of In-flight Countermeasures on Sub-regions of the Hip Bone
Assess Vertebral Compression Fractures (MRID)
SPRINT Optimization Studies
Digital Astronaut: Bone Physiology Model
Risk of Cardiac Rhythm Problems
CV1: What are the in-flight alterations in cardiac structure and function?
Cardiac Atrophy and Diastolic Dysfunction During and After Long Duration Spaceflight: Functional Consequences for Orthostatic Intolerance, Exercise Capacity, and Risk of Cardiac Arrhythmias
Impact of Long Duration Space Flight On Cardiac Structure and Function
Molecular mechanisms underlying heart failure and arrythmias in astronauts (1-year NSBRI Postdoctoral Fellowship)
Cardiovascular and Metabolic Consequences of Circadian Misalignment (NSBRI Postdoctoral Fellowship)
The Multisystem Effect of Exercise Training/Nutritional Support During Prolonged Bed Rest Deconditioning: An Integrative Approach to Countermeasure Development for the Heart, Lungs, Muscles and Bones
Echocardiographic Assessment of Cardiovascular Adaptation and Countermeasures in Microgravity
CV7: How are fluids redistributed in flight?
Bracelet Investigation
Fluid distribution animal study: bone loss, venous pressure, cerebral blood flow, lower limb arteriole atrophy
Validation of On-Orbit Methodology for the Assessment of Cardiac Function and Changes in the Circulating Volume Using Ultrasound and Braslet-M Occlusion Cuffs, SDTO 17011 U/R
Distribution of Body Fluids during Long Duration Space Flight and Subsequent Effects on Intraocular Pressure and Vision Disturbance
Fluid Distribution before, during and after Prolonged Space Flight
Microgravity Associated Compartmental Equilibration (MACE)
CV8: Can manifestations of sub-clinical or environmentally induced cardiovascular diseases during spaceflight be predicted?
Animal radiation study
Identification of cardiometabolic vulnerabilities caused by effects of synergistic stressors that are commonly encountered during space missions
Defining the relationship between biomarkers of oxidative and inflammatory stress and atherosclerosis risk in astronauts during and after long-duration spaceflight
Effects of high dietary heme iron and radiation on cardiovascular function
Data Mining - Document the Rate of Atherosclerosis in Crew
Effects of emotional stress on the cardiovascular system
Cardiovascular Disease Development - Combination Factors Study
Atherosclerosis Development Study - Countermeasure Development
Proteomic Profiling of Human Heart Tissue Exposed to Microgravity
Targeting NO/IKK Signaling to Counteract Hemodynamic Flow-Dependent Endothelial Dysfunction and Vascular Damage after Space Radiation
N7: What are the potassium, magnesium, and phosphorus changes in relation to cardiovascular issues and bone loss?
Dietary Intake Can Predict and Protect Against Changes in Bone Metabolism During Space Flight and Recovery (Pro-K)
Nutritional Status Assessment: SMO-016E
Evaluation of the effect of short duration spaceflight on hepatic nutrition, oxidative damage, and colon microflora
Biochemistry Profile Surveillance
Risk of Clinically Relevant Unpredicted Effects of Medication
Pharm01 (formerly PH01): We do not know how medications are used during spaceflight.
Pharmacology Database
In-Flight Medication Utilization Data Mining
Medication and Symptom Tracking Tool
Clinical Trial and FDA Approved Technology Watch
FDA Adverse Event Report Monitoring
Pharm02 (formerly PH09): We do not know how long medications may be safe and effective beyond their expiration dates.
FDA Comprehensive Stability Evaluation of Three Medications
Packaging Tech Watch
Evaluation of Packaging Materials and Methods for Improved Medication Stability
In-Flight Medication Stability Analysis Method
Stability Analysis of ISS Medications
Pharmacology Database
Pharm03 (formerly PH07 & PH10): We do not know the extent to which spaceflight alters pharmacokinetics.
Effect of Spaceflight on Expression of Metabolic Enzyme Genes in Mice
Validation of Salivary Sampling for Pharmacokinetic Studies
PK Probes in Spaceflight
PK in Spaceflight: Follow-on Study
Effects Of Radiation and Dietary Iron on Expression of Genes and Proteins Involved In Drug Metabolism
In-Flight Medication Utilization Data Mining
Pharmacology Database
Clinical Trial and FDA Approved Technology Watch
FDA Adverse Event Report Monitoring
Medication and Symptom Tracking Tool
Pharm04 (formerly PH07 & PH10): We do not know the extent to which spaceflight alters pharmacodynamics.
PD in Spaceflight
Pharmacology Database
In-Flight Medication Utilization Data Mining
Effects Of Radiation and Dietary Iron on Expression of Genes and Proteins Involved In Drug Metabolism
Clinical Trial and FDA Approved Technology Watch
FDA Adverse Event Report Monitoring
Medication and Symptom Tracking Tool
Pharm05 (formerly PH15): We do not know the extent to which current antimicrobial therapies are effective against microbes that have been altered by spaceflight.
Efficacy of Antimicrobials on Bacteria Cultured in a Spaceflight Analog
Full Scale Antimicrobial Screening
Flight Antimicrobial Screening
Pharmacology Database
In-Flight Medication Utilization Data Mining
Clinical Trial and FDA Approved Technology Watch
FDA Adverse Event Report Monitoring
Medication and Symptom Tracking Tool
Risk of Compromised EVA Performance and Crew Health Due to Inadequate EVA Suit Systems
EVA 6: What physiological & performance capabilities are required for suited operations?
Subject Characterization Study
Metabolic Cost of Experimental Exercise
Optimization of Astronaut Decompression Sickness Prevention Protocols Using Probabilistic Gas and Bubble Dynamics Models
EVA 7: How do EVA suit design parameters* affect crew health and performance in exploration gravity environments and how can their effects be predicted?
Center of Gravity (CG) Evaluations on POGO, NBL, NEEMO, Parabolic Flight
Joint Characteristics/Mobility Evaluations on POGO, NBL, NEEMO, Parabolic Flight
Suit Mass Evaluations on POGO, NBL, NEEMO, Parabolic Flight
Suit Parameters/Human Performance Predictive Tool
Suit Pressure Evaluations on POGO, NBL, NEEMO, Parabolic Flight
Integrated Parabolic Flight Test: Effects of Center of Gravity & Mass on the Biomechanics, Kinematics, & Operator Compensation of Exploration Tasks in Lunar Gravity
Constellation Program (CxP) EVA Systems Test 3 - Effect of Center of Gravity on Metabolic Costs and Biomechanics of Ambulation in a Planetary Suit
NASA Extreme Environment Mission Operations (NEEMO) - 14 Project: Advanced Extravehicular Activity (EVA) Exploration Activities Study to Assess Human Performance Responses in Partial Gravity Environments "Effect of Center of Gravity on Human Performance in Partial Gravity"
EVA 8: What are the metabolic costs of expected nominal & contingency suited tasks in exploration gravity environments and how can heat produced during exploration EVA effectively be removed?
Comparison of Human Performance During EVA in Partial Gravity Analogs: POGO and ARGOS
Effects of Terrain on Performance
Metabolic Evaluations on POGO, ARGOS
Haughton Mars Project (HMP) Gait Characterization Test
Constellation Program (CxP) EVA Systems Test 3 - Effect of Center of Gravity on Metabolic Costs and Biomechanics of Ambulation in a Planetary Suit
Test and Evaluation of Liquid Cooling Garments
ACES Evaporative Cooling Evaluation
EVA 9: How do EVA duty day work-rest cycles (e.g. long, single vs. short, multiple EVAs/day) impact crew performance & health?
Human Factors Evaluation of Small Pressurized Rover Sleep Stations & Exercise Device
EVA 10: How can biosensors be integrated with advanced tools, biofeedback & information systems to improve EVA crew performance and autonomy?
EVA 11: How do suit fit and suit-human biomechanical interactions affect the likelihood of crew injury?
Spacesuit Trauma Countermeasure System for Intravehicular and Extravehicular Activities
2nd Generation Suit Trauma Countermeasure Garment prototype development and testing
Mechanisms of Injury associated with fingertip-pressure in EVA gloves
EVA 13: What is the risk of hypoxia during exploration missions?
Operational Hypoxia Study
Risk of Crew Adverse Health Event Due to Altered Immune Response
IM1: Does spaceflight alter immune function?
Flight-Induced Changes in Immune Defenses-DSO 498
Immune Countermeasures Development
Immune Countermeasures Development – In-flight Validation
Immune dysregulation and clinical risk: >6 month mission duration
Incidence of Latent Virus Shedding During Space Flight-DSO 493
Nutritional Status Assessment: SMO-016E
Space Flight-Induced Reactivation of Latent Epstein-Barr Virus
The Effects of Long-Term Exposure to Microgravity on Salivary Markers of Innate Immunity
Validation of Procedures for Monitoring Crewmember Immune Function (Integrated Immune - SMO 015/SDBI 1900)
Examination of Splenic and Thymic Immune Function in Mice (STS-135 Mouse Tissue Sharing Pilot Study)
Microbial Risk Assessment and Integration
IM2: Is an improved immune standard needed?
Flight-Induced Changes in Immune Defenses-DSO 498
Immune Countermeasures Development
Immune dysregulation and clinical risk: >6 month mission duration
Incidence of Latent Virus Shedding During Space Flight-DSO 493
Microbial Risk Assessment and Integration
Nutritional Status Assessment: SMO-016E
Space Flight-Induced Reactivation of Latent Epstein-Barr Virus
The Effects of Long-Term Exposure to Microgravity on Salivary Markers of Innate Immunity
Validation of Procedures for Monitoring Crewmember Immune Function (Integrated Immune - SMO 015/SDBI 1900)
Examination of Splenic and Thymic Immune Function in Mice (STS-135 Mouse Tissue Sharing Pilot Study)
Biochemistry Profile Surveillance
IM3: Are there suitable analogs for immune dysregulation?
3D Tissue Analogs for the Study of Varicella-Zoster Virulence and Infectivity
Antarctic Winterover Studies - TBD
Apoptosis and Immune Homeostasis During Hindlimb Unloading
Consequences of Long-term Confinement and Hypobaric Hypoxia on Immunity in the Antarctic Concordia Environment (CHOICE)
Immune Analog Validation Studies
Immune Function Changes During a Spaceflight-analog 12-day Undersea Mission (NEEMO IIH ROI)
Bed Rest and Immunity
Flow Cytometer
Identification of cardiometabolic vulnerabilities caused by effects of synergistic stressors that are commonly encountered during space missions
IM5: What is the time course and etiology of immune changes?
Data Sharing Activity to Gather Evidence for Impaired Healing Risk
Flight-Induced Changes in Immune Defenses-DSO 498
Immune Countermeasures Development
Immune dysregulation and clinical risk: >6 month mission duration
Incidence of Latent Virus Shedding During Space Flight-DSO 493
Microbial Risk Assessment and Integration
Nutritional Status Assessment: SMO-016E
Space Flight-Induced Reactivation of Latent Epstein-Barr Virus
The Effects of Long-Term Exposure to Microgravity on Salivary Markers of Innate Immunity
Validation of Procedures for Monitoring Crewmember Immune Function (Integrated Immune - SMO 015/SDBI 1900)
Examination of Splenic and Thymic Immune Function in Mice (STS-135 Mouse Tissue Sharing Pilot Study)
Biochemistry Profile Surveillance
IM6: What are the cumulative effects of chronic immune dysfunction on missions greater than six months?
Immune dysregulation and clinical risk: >6 month mission duration
Consequences of Long-term Confinement and Hypobaric Hypoxia on Immunity in the Antarctic Concordia Environment (CHOICE)
Immune Countermeasures Development – In-flight Validation
Antarctic Winterover Studies - TBD
IM7: What is the correlation of observed laboratory immune changes during spaceflight with known clinical conditions?
Immune/Viral/Nutritional Interrelationship Studies
Clinical Immunology Study - European Collaboration
IM8: What is the correlation of immune risks with other risks, particularly psychological stress, physical deconditioning, nutrition and/or radiation?
Identification of cardiometabolic vulnerabilities caused by effects of synergistic stressors that are commonly encountered during space missions
Nutritional Status Assessment: SMO-016E
Microbial Risk Assessment and Integration
Evaluation of the combined effects of gamma radiation and high dietary iron on oxidative damage and antioxidant status in rats (Immune Assessment)
Biochemistry Profile Surveillance
Risk of Decompression Sickness
DCS1: We have not defined the acceptable DCS risk with respect to the work efficiency index (WEI) for exploration scenarios.
Definition of Acceptable DCS Risk
DCS2: We do not know the contribution of specific DCS risk factors to the development of DCS in the Space Flight Exploration Environment.
Mechanisms of Musculoskeletal-Induced Nucleation in Altitude Decompressions Stress
Prevalence of Venous Gas Emboli after Depressurization in Microgravity
Nitrogen (N2) Elimination
Intermittent Recompression
Animal Model to Evaluate DCS
Abbreviated Purge
Improved Bubble Detection for EVA
DCS3: We do not know the mission related factors that contribute to DCS risk.
Exploration EVA Characterization
Develop and test EVA Workload Simulator
Develop and test EVA Workload Simulator for Exploration
DCS4: We do not know to what extent physiological and environmental factors can be incorporated and validated in a model of DCS for micro and reduced gravity.
Develop and Evaluate Risk Model for DCS
Develop and Evaluate Treatment Model for DCS
DCS5: We do not know what validated procedures will adequately prevent DCS.
PB Accept/Reject Limits
Exploration Atmosphere Prebreathe Validation
ISS Airlock Exploration Atmosphere and PB Verification
DCS6: We do not know what new developments related to DCS will come from other investigators.
DCS Tech Watch
DCS7: We have not validated procedures to adequately treat DCS in the spaceflight environment should it occur.
Long Term Consequences of Spaceflight DCS
Data Mining for Development of Spaceflight DCS Treatment Model
Risk Of Early Onset Osteoporosis Due To Spaceflight
Osteo 1: A new acceptable bone health standard using an improved surrogate for bone strength needs to be defined for the flight environment.
Developing a new bone medical standard for long-duration astronauts based on bone strength estimated by Finite Element [FE] Modeling
Astronaut Bone Medical Standards Derived from Finite Element [FE] Modeling of QCT Scans from Populations Studies
Feasibility Study: QCT Modality for Risk Surveillance of Bone - Effects of In-flight Countermeasures on Sub-regions of the Hip Bone
Osteo 2 (B1a & B29): What is the incidence & prevalence of early onset osteoporosis or fragility fractures due to exposure to spaceflight.
Epidemiologic Analyses of Risk Factors for Bone Loss and Recovery Related to Long Duration Space Flight
Bone Epidemiologic Analysis II
Feasibility Study: QCT Modality for Risk Surveillance of Bone - Effects of In-flight Countermeasures on Sub-regions of the Hip Bone
Assess Vertebral Compression Fractures (MRID)
Osteo 3 (B1b & B29): We need a validated clinically relevant method for assessing the effect of spaceflight on osteoporosis or fracture risk in long-duration astronauts.
Feasibility Study: QCT Modality for Risk Surveillance of Bone - Effects of In-flight Countermeasures on Sub-regions of the Hip Bone
Assess Vertebral Compression Fractures (MRID)
Bone Measures Add-On to OP Summit Follow-On Study
Osteo 4 (B1c, B11, N7): We don't know the contribution of each risk factor on bone loss and recovery of bone strength, and which factors are the best targets for countermeasure application.
Epidemiologic Analyses of Risk Factors for Bone Loss and Recovery Related to Long Duration Space Flight
Bone Epidemiologic Analysis II
Feasibility Study: QCT Modality for Risk Surveillance of Bone - Effects of In-flight Countermeasures on Sub-regions of the Hip Bone
Astronaut Bone Medical Standards Derived from Finite Element [FE] Modeling of QCT Scans from Populations Studies
Nutritional Status Assessment: SMO-016E
SPRINT Optimization Studies
An Integrated Musculoskeletal Countermeasure Battery for Long-Duration Lunar Missions
Dietary Intake Can Predict and Protect Against Changes in Bone Metabolism During Space Flight and Recovery (Pro-K)
Evaluate n-3 Fatty Acids as a Countermeasure for Bone Loss
Bisphosphonates as a Countermeasure to Space Flight Induced Bone Loss: SMO-021
Bone Turnover Model: Initial Implementation
Contribution of the Vestibular and Sympathetic Nervous Systems to Space-Induced Bone Loss (NSBRI Postdoctoral Fellowship)
Contributors to Long-Term Recovery of Bone Strength following Exposure to Microgravity
Evaluation of a sclerostin antibody in mice as a novel promoter of bone formation during spacefllight
Ground-based Biomechanical Analyses of Resistance Exercise Using the Advanced Resistive Exercise Device
Induction of Early Stages of Osteoarthritis After Exposure to Microgravity (NSBRI Postdoctoral Fellowship)
Integrated Resistance and Aerobic Training Study
Maintaining Musculoskeletal Health in the Lunar Environment
Pilot Studies of Radiation Damage in Organ Tissues of Mice
Recovery of Musculoskeletal Quantity and Quality upon Multiple Microgravity Exposure
Simulated Microgravity and Radiation-Induced Bone Degeneration: Oxidative Stress- and p53-Dependent Mechanisms
Space Radiation and Bone Loss: Lunar Outpost Mission Critical Scenarios and Countermeasures
Testosterone Supplementation as a Countermeasure against Musculoskeletal Losses during Space Exploration
Issues Related to Systemic Inflammatory Response
Flywheel Prescription Optimization
Development of New Exercise Hardware for Exploration Missions
Biochemistry Profile Surveillance
Integrated Regulation of Bone and Muscle Metabolism by Simulated Microgravity
Simulated space radiation and weightlessness: vascular-bone coupling mechanisms to preserve skeletal health
Osteo 5 (B10): We need an inflight capability to monitor bone turnover and bone mass changes during spaceflight.
Nutritional Status Assessment: SMO-016E
Flexible Ultrasound – Correlation to Bone Measures
Validation of Bone Microarchitecture Technology – Animal Study
Validation of Bone Microarchitecture Technology – Ground Study
Validation of Bone Microarchitecture Technology – Flight Study
Feasibility Study: QCT Modality for Risk Surveillance of Bone - Effects of In-flight Countermeasures on Sub-regions of the Hip Bone
Monitoring of Bone Loss Biomarkers in Human Sweat: A Non-Invasive, Time Efficient Means of Monitoring Bone Resorption Markers under Micro and Partial Gravity Loading Conditions
Rapid measurements of bone loss using tracer-less calcium isotope analysis of blood and urine
Reusable Handheld Electrolytes and Lab Technology for Humans
A Scanning Confocal Acoustic Diagnostic System for Non-Invasively Assessing Bone Quality
Combined Scanning Confocal Ultrasound Diagnostic and Treatment System for Bone Quality Assessment and Fracture Healing
Wideband Single Crystal Transducer for Bone Characterization
Biochemistry Profile Surveillance
Osteo 6: How do skeletal changes due to spaceflight modify the terrestrial risk of osteoporotic fractures?
Feasibility Study: QCT Modality for Risk Surveillance of Bone - Effects of In-flight Countermeasures on Sub-regions of the Hip Bone
Epidemiologic Analyses of Risk Factors for Bone Loss and Recovery Related to Long Duration Space Flight
Bone Epidemiologic Analysis II
Astronaut Bone Medical Standards Derived from Finite Element [FE] Modeling of QCT Scans from Populations Studies
Assess Vertebral Compression Fractures (MRID)
Bisphosphonates as a Countermeasure to Space Flight Induced Bone Loss: SMO-021
Combined Scanning Confocal Ultrasound Diagnostic and Treatment System for Bone Quality Assessment and Fracture Healing
Osteo 7 (B3, MO5, B15): We need to identify options for mitigating early onset osteoporosis before, during and after spaceflight.
Feasibility Study: QCT Modality for Risk Surveillance of Bone - Effects of In-flight Countermeasures on Sub-regions of the Hip Bone
Bisphosphonates as a Countermeasure to Space Flight Induced Bone Loss: SMO-021
Emerging Drug (DMab) Analogue Validation
Emerging Drug (DMab) Flight Validation
Emerging Drug (TBD) Analogue Validation
Emerging Drug (TBD) Flight Validation
Nutritional Status Assessment: SMO-016E
Integrated Resistance and Aerobic Training Study
Integrated Resistance and Aerobic Exercise Training with Small Compact Exercise Equipment
Epidemiologic Analyses of Risk Factors for Bone Loss and Recovery Related to Long Duration Space Flight
Bone Epidemiologic Analysis II
Evaluate n-3 Fatty Acids as a Countermeasure for Bone Loss
Flight Validation of an Integrated Nutritional, Pharmaceutical and Exercise CM
Pharmaceutical Countermeasure Effects on Tissue-level Quality of Immobilized Bone
Risk of Impaired Control of Spacecraft, Associated Systems and Immediate Vehicle Egress Due to Vestibular/Sensorimotor Alterations Associated with Space Flight
SM1: What is the relationship between in-flight exercise and postflight sensorimotor performance?
Recovery Data Mining: Relationship Between In-Flight Exercise and Postflight Sensorimotor Performance.
Data mining activities for Sensorimotor Discipline
SM2: What are the effects of long-duration spaceflight on sensorimotor function over a crewmember’s lifetime? What are the changes in sensorimotor function over the course of a mission?
Expanded Longitudinal Assessment of Crew Sensorimotor Function
Physiological Factors Contributing to Postflight Changes in Functional Performance
Sensorimotor Assessment and Rehabilitation Apparatus: Procedures and Equipment
Spatial Reorientation of Sensorimotor Balance Control in Altered Gravity
Data mining activities for Sensorimotor Discipline
Straight Ahead in Microgravity
The Role of Tactile Sensation on Locomotor Adaptation in Astronauts Returning from Long Duration Space Flights
Neuroscience Operational and Functional Field Test
SM4: What is the correlation between previous performance data with clinical observations?
Performance Data Mining: Correlation Between Previous Performance Data with Clinical Observations.
SM6: Can a seated manual/visual performance assessment after long-duration spaceflight be completed?
(ZAG/Otolith) Ambiguous Tilt and Translation Motion Cues After Spaceflight/ Otolith Assessment During Postflight Re-adaptation
Assessment of Operator Proficiency Following Long-Duration Spaceflight
Development of Countermeasures to Aid Functional Egress from the Crew Exploration Vehicle Following Long-Duration Spaceflight
Development of Countermeasures to Enhance Sensorimotor Adaptation
Galvanic Vestibular Stimulation (GVS) as an Analogue of Post-flight Sensorimotor Dysfunction
Development of Countermeasures to Enhance Sensorimotor Adaptation - ISS Flight Validation
Robust Human-System Interface Design for Spaceflight-Induced Environments
Head-Eye Coordination during Simulated Orbiter Landings
Sensorimotor adaptation following exposure to ambiguous inertial motion cues
Promoting Sensorimotor Response Generalizability: A Countermeasure to Mitigate Locomotor Dysfunction After Long-Duration Spaceflight
New SMS Countermeasures in a Flight Analog
New SMS Countermeasures in Spaceflight
SM7: Can an integrated post-flight functional task performance test be used on returning ISS crew members to obtain performance decrements?
Physiological Factors Contributing to Postflight Changes in Functional Performance
Extended Performance Tasks
SM12: Develop standards for spaceflight cockpit displays and inputs.
Advanced Displays for Efficient Training and Operation of Robotic Systems
Sensorimotor Displays and Controls to Enhance the Safety of Human/Machine Cooperation During Lunar Landing
Robust Human-System Interface Design for Spaceflight-Induced Environments
SM24: Can individual capacity to produce adaptive change in sensorimotor function to transitions in gravitational environments be predicted with preflight tests of sensorimotor adaptability?
Developing Predictive Measures of Sensorimotor Adaptability to Produce Customized Countermeasure Prescriptions
Developing Predictors of Sensorimotor Adaptability - ISS Flight Validation
Neurovestibular Aspects of Short-radius Artificial Gravity: Toward Comprehensive Counter Measure
SM26: Does exposure to long-duration spaceflight lead to neural structural alterations and does this remodeling impact cognitive and functional performance?
Spaceflight Effects on Neurocognitive Performance: Extent, Longevity, and Neural Bases
Bed Rest as a Spaceflight Analog to Study Neurocognitive Changes: Extent, Longevity, and Neural Bases
Inner Ear Otoconia Response in Mice to Micro- and Hyper-gravity
Potential Impact of Neural Structural Changes after Long-Duration Spaceflight on Cognitive and Functional Performance
BMed3: What aspects, if any, of cognitive performance change in-flight? If there are changes, do they persist post mission? If so, for how long?
Antarctic Long Duration Neurostructural Change (NRA)
Detection & Prevention of Neurobehavioral Vulnerability to Space Radiation
Evidence Review: Cognition in Long Duration Missions in Isolated, Confined and Extreme Environments
Integrated Workshop (Sensorimotor/SHFE/Sleep) Decision Point
NSCOR (TBD)
Speech monitoring of cognitive deficits and stress
Detection and Prevention of Neurobehavioral Vulnerability to Space Radiation
Mitigating Neurobehavioral Vulnerabilities to Space Radiation (Postdoctoral Fellowship)
Spaceflight Effects on Neurocognitive Performance: Extent, Longevity, and Neural Bases
BMed5: What individual characteristics predict successful adaptation and performance in an isolated, confined and extreme environment, especially for long duration missions?
South Pole Station: An Analogue for Human Performance During Long Duration Missions to Isolated and Confined Environments
Evidence Review on Identification of Psychosocial Characteristics in ICE Environments
Investigation into underlying mechanisms re: individual differences in adaptation (NRA)
Investigation into underlying mechanisms re: individual differences in adaptation (RR)
Meta-Analysis of the effects of ICE environments
Synthesis of all Meta-Analyses related to the effects of ICE environments on Subjective Well-Being
Growth and Resiliency Review
The Prediction of the Onset of Anxiety Disorders
White Paper on the Onset of Depression
Markers of Susceptibility to Neurobehavioral Decrements in Space Flight
BMed4: What are the most effective methods for detecting and assessing cognitive performance during exploration missions?
CogGauge: A Cognitive Assessment Tool (Phase II)
CogGauge: A Cognitive Assessment Tool (Phase III)
CogGauge Enhancement
Team Cohesion and Cognition (fMRI) Literature Review
Individualized Real-Time Neurocognitive Assessment Toolkit for Space Flight Fatigue
Risk of Impaired Performance Due to Reduced Muscle Mass, Strength and Endurance
M1: What is the current state of knowledge regarding exercise performance?
M2: What is the current status of in-flight and post-flight exercise performance capability?
Modulation of Muscle Function by Lower Limb Loading during Space Flight - Flight
Reliability of the Power Cycle: A Comparsion to Current NASA Exercise Laboratory Muscle Performance Tests
Modulation of Muscle Function by Lower Limb Loading during Space Flight
M3: What tasks will be required for Exploration missions?
Biomechanical Analysis of Treadmill Locomotion on the International Space Station
Ground-based Biomechanical Analyses of Resistance Exercise Using the Advanced Resistive Exercise Device
Standardized “Pre-flight” Exercise Tests to Predict Performance during Extravehicular Activities in a Lunar Environment
Extended Performance Tasks
Physiological Factors Contributing to Postflight Changes in Functional Performance
Space Suit Simulator (S3) for Partial Gravity EVA Experimentation and Testing
M4: What are the physiologic costs of Exploration mission tasks?
Biomechanical Analysis of Treadmill Locomotion on the International Space Station
Ground-based Biomechanical Analyses of Resistance Exercise Using the Advanced Resistive Exercise Device
Standardized “Pre-flight” Exercise Tests to Predict Performance during Extravehicular Activities in a Lunar Environment
Physiological Factors Contributing to Postflight Changes in Functional Performance
Extended Performance Tasks
Space Suit Simulator (S3) for Partial Gravity EVA Experimentation and Testing
Development of a Submaximal Cycling Protocol to Identify the Ventilatory Threshold in Astronauts: Application to Monitor Changes in Endurance Capacity in Response to Long-Duration Spaceflight Missions
M6: Can a standardized performance measure of readiness for Exploration mission tasks be developed?
Biomechanical Analysis of Treadmill Locomotion on the International Space Station
Ground-based Biomechanical Analyses of Resistance Exercise Using the Advanced Resistive Exercise Device
Extended Performance Tasks
Standardized “Pre-flight” Exercise Tests to Predict Performance during Extravehicular Activities in a Lunar Environment
Physiological Factors Contributing to Postflight Changes in Functional Performance
Reliability of the Power Cycle: A Comparsion to Current NASA Exercise Laboratory Muscle Performance Tests
M7: Can the current in-flight performance be maintained with reduced exercise volume?
Biomechanical Analysis of Treadmill Locomotion on the International Space Station
Ground-based Biomechanical Analyses of Resistance Exercise Using the Advanced Resistive Exercise Device
Integrated Endurance and Resistance Exercise Countermeasures Using a Gravity Independent Training Device
Integrated Resistance and Aerobic Exercise Training with Small Compact Exercise Equipment
Flywheel Prescription Optimization
Development of New Exercise Hardware for Exploration Missions
A New Harness For Use with Exercise Countermeasures-Validation of Improved Comfort and Loading with the Center for Space Medicine (CSM) Harness
Testosterone Supplementation as a Countermeasure against Musculoskeletal Losses during Space Exploration
Exercise Plus Nutritional Supplement Studies
Integrated Resistance and Aerobic Training Study
SPRINT Optimization Studies
Hydration Effects on Muscle
Gender Effects on Muscle
Flight Validation Studies of Exercise + Pharmaceutical or Nutritional Supplements
ESPRIT: Exercise Sensing and Pose Recovery Inference Tool
Enhancing the Efficacy of Musculoskeletal Countermeasures Using Computer Simulation
Reliability of the Power Cycle: A Comparsion to Current NASA Exercise Laboratory Muscle Performance Tests
Effect of Prolonged Space Flight on Human Skeletal Muscle
Force Regulation As a Countermeasure To Muscle Atrophy
Time Course of Metabolic Adaptations During Loading and Unloading
The Constant Force Resistive Exercise Unit (CFREU) for Multi-Functional Exercise
Evaluation of Maximal Oxygen Consumption (VO2pk) Protocols for Determining Ventilatory Threshold
M8: What is the minimum exercise regimen needed to maintain fitness levels for tasks?
Biomechanical Analysis of Treadmill Locomotion on the International Space Station
Ground-based Biomechanical Analyses of Resistance Exercise Using the Advanced Resistive Exercise Device
Integrated Endurance and Resistance Exercise Countermeasures Using a Gravity Independent Training Device
Integrated Resistance and Aerobic Exercise Training with Small Compact Exercise Equipment
Flywheel Prescription Optimization
Development of New Exercise Hardware for Exploration Missions
A New Harness For Use with Exercise Countermeasures-Validation of Improved Comfort and Loading with the Center for Space Medicine (CSM) Harness
Testosterone Supplementation as a Countermeasure against Musculoskeletal Losses during Space Exploration
Exercise Plus Nutritional Supplement Studies
Integrated Resistance and Aerobic Training Study
SPRINT Optimization Studies
Gender Effects on Muscle
Hydration Effects on Muscle
Flight Validation Studies of Exercise + Pharmaceutical or Nutritional Supplements
Integrate deadlift biomechanics model with ARED device model
Integrate Biomechanics and ARED device modules
ESPRIT: Exercise Sensing and Pose Recovery Inference Tool
Enhancing the Efficacy of Musculoskeletal Countermeasures Using Computer Simulation
Reliability of the Power Cycle: A Comparsion to Current NASA Exercise Laboratory Muscle Performance Tests
Effect of Prolonged Space Flight on Human Skeletal Muscle
Force Regulation As a Countermeasure To Muscle Atrophy
Time Course of Metabolic Adaptations During Loading and Unloading
The Constant Force Resistive Exercise Unit (CFREU) for Multi-Functional Exercise
Evaluation of Maximal Oxygen Consumption (VO2pk) Protocols for Determining Ventilatory Threshold
M9: What is the minimum set of exercise hardware needed to maintain those (M8) fitness levels?
Biomechanical Analysis of Treadmill Locomotion on the International Space Station
Ground-based Biomechanical Analyses of Resistance Exercise Using the Advanced Resistive Exercise Device
Integrated Endurance and Resistance Exercise Countermeasures Using a Gravity Independent Training Device
Integrated Resistance and Aerobic Exercise Training with Small Compact Exercise Equipment
Flywheel Prescription Optimization
Development of New Exercise Hardware for Exploration Missions
A New Harness For Use with Exercise Countermeasures-Validation of Improved Comfort and Loading with the Center for Space Medicine (CSM) Harness
Testosterone Supplementation as a Countermeasure against Musculoskeletal Losses during Space Exploration
Exercise Plus Nutritional Supplement Studies
Integrated Resistance and Aerobic Training Study
SPRINT Optimization Studies
Hydration Effects on Muscle
Gender Effects on Muscle
Flight Validation Studies of Exercise + Pharmaceutical or Nutritional Supplements
Integrate deadlift biomechanics model with ARED device model
Integrate Biomechanics and ARED device modules
ESPRIT: Exercise Sensing and Pose Recovery Inference Tool
Enhancing the Efficacy of Musculoskeletal Countermeasures Using Computer Simulation
Reliability of the Power Cycle: A Comparsion to Current NASA Exercise Laboratory Muscle Performance Tests
Effect of Prolonged Space Flight on Human Skeletal Muscle
Force Regulation As a Countermeasure To Muscle Atrophy
Time Course of Metabolic Adaptations During Loading and Unloading
The Constant Force Resistive Exercise Unit (CFREU) for Multi-Functional Exercise
Evaluation of Maximal Oxygen Consumption (VO2pk) Protocols for Determining Ventilatory Threshold
Compact, Controlled Force Crew Exercise System
M14: What anabolic or anti-catabolic drugs can be used to mitigate muscle loss?
Testosterone Supplementation as a Countermeasure against Musculoskeletal Losses during Space Exploration
Anabolic/Anti-Catabolic Pharmaceutical(s) with or without Exercise Studies - TBD
Flight Validation Studies of Exercise + Pharmaceutical or Nutritional Supplements
M23: Do factors in addition to unloading contribute to muscle atrophy during space flight (e.g. radiation, inflammation, hydration, redox balance, energy balance)?
Gender Effects on Muscle
Role of Energy Balance in Maintaining Muscle and Bone
Loading-Independent Factors that Contribute to Spaceflight-Induced Muscle Loss
Redox Modulation of Skeletal Muscle Function in Microgravity
M24: What is the time course of changes in muscle protein turnover, muscle mass and function during long term space flight?
Determination of the Time Course of Muscle Adaptations to Long Duration Space Flight
Determination of Muscle Protein Turnover During Long Duration Space Flight
Modulation of Muscle Function by Lower Limb Loading during Space Flight - Flight
Modulation of Muscle Function by Lower Limb Loading during Space Flight
N9: What are the interactions of exercise and nutrition in altered weight bearing environments that mitigate muscle loss (Muscle)?
Exercise Plus Nutritional Supplement Studies
Hydration Effects on Muscle
An Integrated Low-Volume Nutritional Countermeasure to Maintain Muscle Mass and Function During Space Exploration
Flight Validation Studies of Exercise + Pharmaceutical or Nutritional Supplements
SM7: Can an integrated post-flight functional task performance test be used on returning ISS crew members to obtain performance decrements?
Physiological Factors Contributing to Postflight Changes in Functional Performance
Extended Performance Tasks
Risk of Injury from Dynamic Loads
OP1: How do we protect the crew from injury during dynamic phases of flight?
Occupant Protection Data Mining and Modeling Project
Comparison of Biodynamics Models Using Automotive Racing Crash Data
Deconditioning Summit
Deconditioning Summit Follow-On Study
EFT-1 Modeling
EM-1 Data Collection and Modeling
EM-2 Modeling
Human Volunteer Testing
Risk of Intervertebral Disk Damage
B4: What is the incidence of intervertebral disk damage following spaceflight?
Data Mining for Intervertebral Disk Damage
Risk of Intervertebral Disc Damage After Prolonged Spaceflight
Sonographic Astronaut Vertebral Examination
Risk of Orthostatic Intolerance During Re-Exposure to Gravity
CV3: Is orthostatic intolerance a potential hazard?
Distribution of Body Fluids during Long Duration Space Flight and Subsequent Effects on Intraocular Pressure and Vision Disturbance
Impact of Long Duration Space Flight On Cardiac Structure and Function
Efficacy of JOBST Compression Garments to Prevent Orthostatic Intolerance for up to Three Days following 14 Days of Bed Rest
Evaluation of Commercial Compression Garments as a Countermeasure to Post-Spaceflight Orthostatic Intolerance (OIG DSO641)
Artificial Gravity Exposure Effects on Cardiovascularly Deconditioned Women's and Men's Orthostatic Intolerance Limit
EXAMINING INDIVIDUAL DIFFERENCES IN TEMPORAL PROFILES OF CARDIOVASCULAR RESPONSES TO HEAD DOWN TILT DURING FLUID LOADING
Improved Fluid Loading II
ISS as Exploration Analog -Cardio Study
Gender Differences in Bedrest: Autonomic and Neuroendocrine Changes and Vascular Responses in Lower and Upper Extremities
Evaluation of Compression Garments as Countermeasures to Orthostatic Intolerance
Hypovolemia as a Model of Space Flight
Test of Midodrine as a Countermeasure against Postflight Orthostatic Hypotension: SMO-006
Vestibular-Cerebrovascular Interaction and their Contribution to Post-Spaceflight Orthostatic Intolerance
Echocardiographic Assessment of Cardiovascular Adaptation and Countermeasures in Microgravity
Neuroscience Operational and Functional Field Test
CV4: Is 1/6-g exposure protective of 1-g orthostatic tolerance?
Lunar Analog Bed Rest Development
Lunar analog pilot study
Risk of Reduced Physical Performance Capabilities Due to Reduced Aerobic Capacity
CV2: What is VO2max in-flight and immediately post-flight?
Maximal Oxygen Uptake (VO2max) and Submaximal Estimates of VO2max Before, During and After Long Duration International Space Station Missions
New aerobic measures/functional correlates
Hypovolemia as A Model Of Space Flight: Cardiovascular Exercise Effects and Countermeasures
Echocardiographic Assessment of Cardiovascular Adaptation and Countermeasures in Microgravity
M7: Can the current in-flight performance be maintained with reduced exercise volume?
Biomechanical Analysis of Treadmill Locomotion on the International Space Station
Ground-based Biomechanical Analyses of Resistance Exercise Using the Advanced Resistive Exercise Device
Integrated Endurance and Resistance Exercise Countermeasures Using a Gravity Independent Training Device
Integrated Resistance and Aerobic Exercise Training with Small Compact Exercise Equipment
Flywheel Prescription Optimization
Development of New Exercise Hardware for Exploration Missions
A New Harness For Use with Exercise Countermeasures-Validation of Improved Comfort and Loading with the Center for Space Medicine (CSM) Harness
Testosterone Supplementation as a Countermeasure against Musculoskeletal Losses during Space Exploration
Exercise Plus Nutritional Supplement Studies
Integrated Resistance and Aerobic Training Study
SPRINT Optimization Studies
Hydration Effects on Muscle
Gender Effects on Muscle
Flight Validation Studies of Exercise + Pharmaceutical or Nutritional Supplements
ESPRIT: Exercise Sensing and Pose Recovery Inference Tool
Enhancing the Efficacy of Musculoskeletal Countermeasures Using Computer Simulation
Reliability of the Power Cycle: A Comparsion to Current NASA Exercise Laboratory Muscle Performance Tests
Effect of Prolonged Space Flight on Human Skeletal Muscle
Force Regulation As a Countermeasure To Muscle Atrophy
Time Course of Metabolic Adaptations During Loading and Unloading
The Constant Force Resistive Exercise Unit (CFREU) for Multi-Functional Exercise
Evaluation of Maximal Oxygen Consumption (VO2pk) Protocols for Determining Ventilatory Threshold
M8: What is the minimum exercise regimen needed to maintain fitness levels for tasks?
Biomechanical Analysis of Treadmill Locomotion on the International Space Station
Ground-based Biomechanical Analyses of Resistance Exercise Using the Advanced Resistive Exercise Device
Integrated Endurance and Resistance Exercise Countermeasures Using a Gravity Independent Training Device
Integrated Resistance and Aerobic Exercise Training with Small Compact Exercise Equipment
Flywheel Prescription Optimization
Development of New Exercise Hardware for Exploration Missions
A New Harness For Use with Exercise Countermeasures-Validation of Improved Comfort and Loading with the Center for Space Medicine (CSM) Harness
Testosterone Supplementation as a Countermeasure against Musculoskeletal Losses during Space Exploration
Exercise Plus Nutritional Supplement Studies
Integrated Resistance and Aerobic Training Study
SPRINT Optimization Studies
Gender Effects on Muscle
Hydration Effects on Muscle
Flight Validation Studies of Exercise + Pharmaceutical or Nutritional Supplements
Integrate deadlift biomechanics model with ARED device model
Integrate Biomechanics and ARED device modules
ESPRIT: Exercise Sensing and Pose Recovery Inference Tool
Enhancing the Efficacy of Musculoskeletal Countermeasures Using Computer Simulation
Reliability of the Power Cycle: A Comparsion to Current NASA Exercise Laboratory Muscle Performance Tests
Effect of Prolonged Space Flight on Human Skeletal Muscle