Active - Task currently funded
There are no procedures currently in place to monitor immune function or its effect on crew health. Immune dysregulation has been demonstrated to occur during spaceflight, yet little in-flight immune data has been generated to assess whether or not this may be a clinical problem. This SMO will assess the clinical risks resulting from the adverse effects of space flight on the human immune system and will validate a flight-compatible immune monitoring strategy. The correlation between in-flight immunity, physiological stress and a measurable clinical outcome (viral reactivation) will be determined for long- vs. short-duration space flight.
The objective of this Supplemental Medical Objective (SMO) is 1) to develop and validate an immune monitoring strategy consistent with operational flight requirements and constraints.