Concern of Intervertebral Disc Damage upon and immediately after re-exposure to Gravity
Short Title: IVD
03/04/15 01:16:39 PM (Central)
Element: Human Health Countermeasures
RMAT Report Not Available
|Deep Space Journey
Given the morphological and possible biochemical changes in the IVD (intervertebral disc) during mechanical unloading in space, there is the possibility of IVD damage upon and immediately after re-exposure to gravity (1/6, 3/8 or 1G).
The Concern Item does not have a Context (not an HSRB requirement).
Although the incidence of IVD injury is higher in astronauts compared to a matched control group not involved in spaceflight, the risk for IVD injury due to spaceflight still requires evidence. The 2009 NASA Research Announcement was utilized to solicit and select proposals to gather data to increase understanding as to the etiology of IVD injury due to spaceflight. Once data are collected to describe spaceflight effects on IVD morphology and the contribution from risk factors, the data will be presented to the Human System Risk Forum to decide if countermeasures need to be developed.