Short Title:
Responsible HRP Element:
Space Human Factors and Habitability
Funding Status:
Planned - Task expected to be within budget
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Procurement Mechanism(s):
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| NASA Research Announcement |
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Aims:
The aims of the Host Microbe Interaction Studies are:
• Concurrently investigate alterations in a relevant human surrogate host model, an infectious pathogen, and the interaction between the two, in a spaceflight analog environment.
• Elucidate the cellular and molecular mechanism(s) behind the alterations.
• Relate the observed alterations to other pathogens that may be of interest to the space program.
Integration/Unique Aspects:
Gaps supported by this task include AEH7, AEH8, AEH 9, and AEH 10
Flight Resources
| Number of Subjects
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0
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| When are operations required?
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Pre/In/Post
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| When is an approved proposal expected?
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3/31/2014
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Frequency and type of in-flight sessions:
N/A
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Type of in-flight sessions:
Operational activities, such as turning equipment on/off; possible sample transfer
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Type of in-flight sample collection:
Sample collection possible from cultures, depends upon design.
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Hardware/Software Requirements:
Hardware for culturing microbes
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BDC Requirements:
Sample collection.
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Category:
Risk Characterization/Quantification
Subcategory:
Evidence
Description:
The deliverable is inputs to the Task Book that describe research findings that advance understanding of the influence of the space environment on (1) alterations in pathogens and in the host and (2) the cellular and molecular mechanism(s) of interaction in both the host cells and the microbial cells.
Customer:
SHFH
Is there a signed Customer-Supplier Agreement?
No
Delivery Milestone:
9/28/2018