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VIIP1
VIIP
A data mining project to identify cardiovascular related factors that may contribute to changes in visual acuity within the astronaut corps
(Completed)
Task Book:
Entry Unavailable
Principal Investigator:
Platts, S.
Short Title:
CV Data Mining for VIIP
Responsible HRP Element:
Human Health Countermeasures
Supporting Org(s):
Funding Status:
Completed - Task has been completed
Procurement Mechanism(s):
Direct Contract
Aims:
Integration/Unique Aspects:
Resources
(
None Listed
)
Deliverables (
0
)
Mappings
Risk of Spaceflight-Induced Intracranial Hypertension/Vision Alterations
VIIP1: What is the etiology of visual acuity and ocular structural and functional changes seen in-flight and postflight?
A data mining project to identify cardiovascular related factors that may contribute to changes in visual acuity within the astronaut corps
Related Tasks (52)
Bracelet Investigation
Common Item(s)
Risk of Spaceflight-Induced Intracranial Hypertension/Vision Alterations
Fluid distribution animal study: bone loss, venous pressure, cerebral blood flow, lower limb arteriole atrophy
Common Item(s)
Risk of Spaceflight-Induced Intracranial Hypertension/Vision Alterations
Validation of On-Orbit Methodology for the Assessment of Cardiac Function and Changes in the Circulating Volume Using Ultrasound and Braslet-M Occlusion Cuffs, SDTO 17011 U/R
Common Item(s)
Risk of Spaceflight-Induced Intracranial Hypertension/Vision Alterations
Hindlimb suspension (HS) as an analog model of ocular alterations associated with cephalad fluid shifts: resveratrol as a countermeasure
Common Item(s)
Risk of Spaceflight-Induced Intracranial Hypertension/Vision Alterations
Spaceflight effects on the mouse retina: Histological, gene expression and epigenetic changes after flight on STS-135
Common Item(s)
Risk of Spaceflight-Induced Intracranial Hypertension/Vision Alterations
Pilot study to evaluate a novel non-invasive technology to estimate peripheral and central venous pressure
Common Item(s)
Risk of Spaceflight-Induced Intracranial Hypertension/Vision Alterations
VIIP1: What is the etiology of visual acuity and ocular structural and functional changes seen in-flight and postflight?
rVisual Impairment and Intracranial Pressure Project Data Mining
Common Item(s)
Risk of Spaceflight-Induced Intracranial Hypertension/Vision Alterations
VIIP1: What is the etiology of visual acuity and ocular structural and functional changes seen in-flight and postflight?
Combined effects of gamma radiation and high dietary iron on oxidative damage and antioxidant status in rat eyes
Common Item(s)
Risk of Spaceflight-Induced Intracranial Hypertension/Vision Alterations
Phase I: SD-OCT Analysis of The Optic Nerve Head and Surrounding Structures in Long Duration ISS Crew Members Compared to Terrestrial Bound Normals
Common Item(s)
Risk of Spaceflight-Induced Intracranial Hypertension/Vision Alterations
VIIP1: What is the etiology of visual acuity and ocular structural and functional changes seen in-flight and postflight?
Phase II: D-OCT Analysis of The Optic Nerve Head and Surrounding Structures in Long Duration ISS Crew Members Compared to Terrestrial Bound Normals and Pseudotumor/Increased Intracranial Hypertension Patients
Common Item(s)
Risk of Spaceflight-Induced Intracranial Hypertension/Vision Alterations
VIIP1: What is the etiology of visual acuity and ocular structural and functional changes seen in-flight and postflight?
Prospective Observational Study of Ocular Health in ISS Crews
Common Item(s)
Risk of Spaceflight-Induced Intracranial Hypertension/Vision Alterations
VIIP1: What is the etiology of visual acuity and ocular structural and functional changes seen in-flight and postflight?
Risk of visual impairment and intracranial hypertension after space flight: Evaluation of the role of polymorphism of enzymes involved in one-carbon metabolism
Common Item(s)
Risk of Spaceflight-Induced Intracranial Hypertension/Vision Alterations
VIIP1: What is the etiology of visual acuity and ocular structural and functional changes seen in-flight and postflight?
Are Medications Involved in Vision and Intracranial Pressure Changes Seen in Spaceflight?
Common Item(s)
Risk of Spaceflight-Induced Intracranial Hypertension/Vision Alterations
VIIP1: What is the etiology of visual acuity and ocular structural and functional changes seen in-flight and postflight?
Flight-Vascular Function in the Head/Neck
Common Item(s)
Risk of Spaceflight-Induced Intracranial Hypertension/Vision Alterations
VIIP1: What is the etiology of visual acuity and ocular structural and functional changes seen in-flight and postflight?
SD/On-going VIIP Hardware Techwatch
Common Item(s)
Risk of Spaceflight-Induced Intracranial Hypertension/Vision Alterations
SD/Development of in-flight fundoscopy
Common Item(s)
Risk of Spaceflight-Induced Intracranial Hypertension/Vision Alterations
SD/Fundoscopy Trade Study
Common Item(s)
Risk of Spaceflight-Induced Intracranial Hypertension/Vision Alterations
SD/Development of in-flight diagnostic OCT
Common Item(s)
Risk of Spaceflight-Induced Intracranial Hypertension/Vision Alterations
SD/Diagnostic OCT Trade Study
Common Item(s)
Risk of Spaceflight-Induced Intracranial Hypertension/Vision Alterations
ICP Tech Search (Innocentive, Yet To Come)
Common Item(s)
Risk of Spaceflight-Induced Intracranial Hypertension/Vision Alterations
Effects of Microgravity on Intracranial Pressure
Common Item(s)
Risk of Spaceflight-Induced Intracranial Hypertension/Vision Alterations
VIIP1: What is the etiology of visual acuity and ocular structural and functional changes seen in-flight and postflight?
Analysis of a Clinical Database as a Means to Validate Non-invasive Assessment of Intracranial Pressure Using the Cerebral and Cochlear Fluid Pressure (CCFP) Analyzer
Common Item(s)
Risk of Spaceflight-Induced Intracranial Hypertension/Vision Alterations
SD/Upgrade Visual Acuity Software and In-flight Tonometer
Common Item(s)
Risk of Spaceflight-Induced Intracranial Hypertension/Vision Alterations
Non-invasive ICP device purchase & evaluation
Common Item(s)
Risk of Spaceflight-Induced Intracranial Hypertension/Vision Alterations
Flight validation - Combination Countermeasure for VIIP
Common Item(s)
Risk of Spaceflight-Induced Intracranial Hypertension/Vision Alterations
Ground - Combination Countermeasure for VIIP (Drug + Exercise and/or Mechanical CM)
Common Item(s)
Risk of Spaceflight-Induced Intracranial Hypertension/Vision Alterations
Ground - Aerobic Exercise Countermeasure for VIIIP
Common Item(s)
Risk of Spaceflight-Induced Intracranial Hypertension/Vision Alterations
Drug Countermeasure Flight Validation – Acetazolamide, manipulation of AQP1 and AQP4, Atrial Nateuretic Peptide to decrease ICP, drug to decrease CSF production
Common Item(s)
Risk of Spaceflight-Induced Intracranial Hypertension/Vision Alterations
Ground/Bedrest Drug Countermeasure for VIIP
Common Item(s)
Risk of Spaceflight-Induced Intracranial Hypertension/Vision Alterations
Head-down tilt as a model for intracranial and intraocular pressures, and retinal changes during spaceflight
Common Item(s)
Risk of Spaceflight-Induced Intracranial Hypertension/Vision Alterations
Flight - Contributions of CO2, resistive exercise, and sodium to the VIIP syndrome – effect on cerebrovascular dilation and ICP
Common Item(s)
Risk of Spaceflight-Induced Intracranial Hypertension/Vision Alterations
VIIP1: What is the etiology of visual acuity and ocular structural and functional changes seen in-flight and postflight?
Bedrest – Contributions of CO2, resistive exercise, and sodium to the VIIP syndrome
Common Item(s)
Risk of Spaceflight-Induced Intracranial Hypertension/Vision Alterations
VIIP1: What is the etiology of visual acuity and ocular structural and functional changes seen in-flight and postflight?
Data mining – Contributions of CO2 to the VIIP syndrome
Common Item(s)
Risk of Spaceflight-Induced Intracranial Hypertension/Vision Alterations
VIIP1: What is the etiology of visual acuity and ocular structural and functional changes seen in-flight and postflight?
Pre & Postflight MRV review (central venous congestion)
Common Item(s)
Risk of Spaceflight-Induced Intracranial Hypertension/Vision Alterations
VIIP1: What is the etiology of visual acuity and ocular structural and functional changes seen in-flight and postflight?
Evaluation of increased CSF dynamics (production/absorption) during spaceflight
Common Item(s)
Risk of Spaceflight-Induced Intracranial Hypertension/Vision Alterations
VIIP1: What is the etiology of visual acuity and ocular structural and functional changes seen in-flight and postflight?
Pre and postflight measurement of cerebrospinal fluid (CSF) dynamics (production/absorption)
Common Item(s)
Risk of Spaceflight-Induced Intracranial Hypertension/Vision Alterations
VIIP1: What is the etiology of visual acuity and ocular structural and functional changes seen in-flight and postflight?
Biomarker for identification of increased ICP - Flight Validation
Common Item(s)
Risk of Spaceflight-Induced Intracranial Hypertension/Vision Alterations
VIIP1: What is the etiology of visual acuity and ocular structural and functional changes seen in-flight and postflight?
Biomarker for identification of increased ICP
Common Item(s)
Risk of Spaceflight-Induced Intracranial Hypertension/Vision Alterations
VIIP1: What is the etiology of visual acuity and ocular structural and functional changes seen in-flight and postflight?
Validation of in-flight non-invasive ICP as compared to pre and post lumbar puncture
Common Item(s)
Risk of Spaceflight-Induced Intracranial Hypertension/Vision Alterations
VIIP1: What is the etiology of visual acuity and ocular structural and functional changes seen in-flight and postflight?
Evaluation of spaceflight alterations in neurohumoral control and vascular function changes towards VIIP
Common Item(s)
Risk of Spaceflight-Induced Intracranial Hypertension/Vision Alterations
VIIP1: What is the etiology of visual acuity and ocular structural and functional changes seen in-flight and postflight?
SD/In-flight monitoring of visual health (MRID)
Common Item(s)
Risk of Spaceflight-Induced Intracranial Hypertension/Vision Alterations
VIIP1: What is the etiology of visual acuity and ocular structural and functional changes seen in-flight and postflight?
Ocular structure, biomechanics and translaminar pressure gradients in relation to the VIIP syndrome
Common Item(s)
Risk of Spaceflight-Induced Intracranial Hypertension/Vision Alterations
VIIP1: What is the etiology of visual acuity and ocular structural and functional changes seen in-flight and postflight?
Data Mining – Ocular structure and biomechanics in relation to the VIIP syndrome
Common Item(s)
Risk of Spaceflight-Induced Intracranial Hypertension/Vision Alterations
VIIP1: What is the etiology of visual acuity and ocular structural and functional changes seen in-flight and postflight?
Visual Impairment Intracranial Pressure Risk: Occupational Surveillance Data Mining
Common Item(s)
Risk of Spaceflight-Induced Intracranial Hypertension/Vision Alterations
VIIP1: What is the etiology of visual acuity and ocular structural and functional changes seen in-flight and postflight?
Risk of Spaceflight-Induced Intracranial Hypertension/Vision Alterations Evidence Report
Common Item(s)
Risk of Spaceflight-Induced Intracranial Hypertension/Vision Alterations
VIIP1: What is the etiology of visual acuity and ocular structural and functional changes seen in-flight and postflight?
Microgravity Associated Compartmental Equilibration (MACE)
Common Item(s)
Risk of Spaceflight-Induced Intracranial Hypertension/Vision Alterations
Fluid Distribution before, during and after Prolonged Space Flight
Common Item(s)
Risk of Spaceflight-Induced Intracranial Hypertension/Vision Alterations
Human Cerebral Vascular Autoregulation and Venous Outflow in Response to Microgravity-Induced Cephalad Fluid Redistribution
Common Item(s)
Risk of Spaceflight-Induced Intracranial Hypertension/Vision Alterations
VIIP1: What is the etiology of visual acuity and ocular structural and functional changes seen in-flight and postflight?
Distribution of Body Fluids during Long Duration Space Flight and Subsequent Effects on Intraocular Pressure and Vision Disturbance
Common Item(s)
Risk of Spaceflight-Induced Intracranial Hypertension/Vision Alterations
VIIP1: What is the etiology of visual acuity and ocular structural and functional changes seen in-flight and postflight?
Non-Invasive Monitoring of Intracranial Pressure (ICP) with Volumetric Ophthalmic Ultrasound
Common Item(s)
Risk of Spaceflight-Induced Intracranial Hypertension/Vision Alterations
Comparison of Continuous Non-Invasive and Invasive Intracranial Pressure Measurement
Common Item(s)
Risk of Spaceflight-Induced Intracranial Hypertension/Vision Alterations
Non-invasive ICP Flight Hardware Development
Common Item(s)
Risk of Spaceflight-Induced Intracranial Hypertension/Vision Alterations
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VIIP Schedule
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