Task Functional Role Of The Betaig-H3 Gene In High-Energy Heavy Ions-Induced Carcinogenesis (Completed)
Short Title: Betaig
Responsible HRP Element: Space Radiation
Supporting Org(s):
NASA/Fundamental Space Biology
Funding Status: Completed - Task has been completed
Procurement Mechanism(s):
NASA Research Announcement
Aims:
  1. To establish the tumorigenic cell model by irradiating hTERT-SAEC cells using beams of charged heavy ions;
  2. To demonstrate that loss of Betaig-h3 expression is causally related to the malignant transformation process; and
  3. To generate mouse embryonic stem cells and knock-out mice with disrupted Betaig-h3 gene.
Integration/Unique Aspects:
Mappings