Short Title:
Responsible HRP Element:
Space Human Factors and Habitability
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Supporting Org(s):
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| Space Human Factors Habitability |
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Funding Status:
Completed - Task has been completed
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Procurement Mechanism(s):
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Aims:
OBJECTIVES:
1. Comparison of whole genome microarray-mediated gene expression profiling of Salmonella typhimurium, Pseudomonas aeruginosa, and Candida albicans, in response to spaceflight, to normal gravity controls and when the organisms are grown during suspension culture in modeled microgravity.
2. Determination of the effect of spaceflight on the virulence potential of the pathogenic microorganisms, S. typhimurium, P. aeruginosa, and C. albicans, immediately following their return from spaceflight.
3. Comparison of S. typhimurium cultures grown in nutrient limited media to those grown in nutrient rich media to determine the potential effects of nutritional status on changes in gene expression and virulence properties during spaceflight
Integration/Unique Aspects:
This task support AEH 7 and AEH 9
Flight Resources
| Number of Subjects
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0
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| When are operations required?
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Pre/In/Post
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| When is an approved proposal expected?
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3/1/2005
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Frequency and type of in-flight sessions:
N/A
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Type of in-flight sessions:
Experiment Activation, sample storage
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Type of in-flight sample collection:
sample storage
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Hardware/Software Requirements:
This study, also known as MICROBE, required the Group Activation Pack (GAP), a triple-enclosed containment vessel used to house microbiology experiments in microgravity flown aboard STS 115. Ground-based bioreactors were used in ground studies to simulate microgravity in the laboratory.
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BDC Requirements:
Sample collection
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Category:
Risk Characterization/Quantification
Subcategory:
Evidence
Description:
Final Report
Customer:
SHFH
Is there a signed Customer-Supplier Agreement?
No
Delivery Milestone:
10/19/2010