Gap N4: Does mission architecture and/or available countermeasures impact nutritional status of crewmembers during spaceflight?
Last Published:  03/26/21 03:33:57 PM (Central)
Responsible Element: Human Health Countermeasures (HHC)
Status: Open
Description

Initial State of Gap: This gap is designed to capture the potential impact of future countermeasure options and/or mission architectures. Nutrition SMO data collection has allowed evaluation of nutritional status assessment on ISS crewmembers with access to updated operational countermeasures (e.g., ARED), and participating in multiple countermeasure studies, including Bisphosphonate, Renal Stone, and SPRINT.  These types of data will also be required as other countermeasures are proposed and tested, and will be provided by the Space Biochemistry Profile study. Given the unlimited options for design reference mission architectures, these will need to be evaluated on a case-by-case basis for their impact on nutritional requirements/nutritional status.  For example, factors such as mission length, vehicle atmosphere, EVA frequency, surface gravity, food system design and limitations, resupply options and more all have potential impact on nutrition. 

Interim steps:

    1. Evaluate ongoing Nutritional Status Assessment data collection with each countermeasure tested during flight
    2. Determine if any countermeasure or suite of measures has significant (quantify such as 10% change) impact on any macro or micro nutrient
    3. If any problematic countermeasure is identified determine necessary action for follow-up research or standard update
    4. Interim steps are repeated yearly.  [100% gap completion in 2020; therefore assume 14% closer to gap completion each year from 2013 until 2020]

Approach: Nutrition SMO data collection, of which a subset has been proposed in the Spaceflight Biochemical Profile project, will be required for monitoring of effects of countermeasures on nutritional status. MedB8.1/Clinical Nutritional Status Assessment  also provides valuable pre and postflight information, and inflight dietary intake assessment.  The Integrated Nutrition Countermeasure study is also planned to provide more detailed dietary intake data, which will be critical for this gap.

Target for Closure
Given the multifaceted  nature of nutrition, evaluation of the impact of countermeasures will be required anytime a new countermeasure is tested or applied, and this gap will not close until the end of ISS (estimated 2020).   
Mappings
Risk Risk of Performance Decrement and Crew Illness Due to Inadequate Food and Nutrition
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