Last Published:  04/20/22 11:43:20 AM (Central)
Responsible Element: Human Health Countermeasures (HHC)
Status: Open

Note: Standards may be design reference mission specific.

Initial State:
One purpose of protecting skeletal muscle fitness (e.g. muscle strength, power, endurance) during both short and long duration space flight is to ensure successful completion of mission tasks. Mission tasks may include nominal activities such as EVA performance, or off-nominal situations such as  post-landing emergency egress or assisting an incapacitated crew member. The identification of specific minimum muscle performance fitness thresholds required to perform mission critical tasks will inform mission readiness.  Muscle fitness standards are expected to be Design Reference Mission specific. It is important to note that performance of mission tasks is not the only reason to protect skeletal muscle. Uncontrolled muscle catabolism poses other health related problems.
Interim Stages:
Identification of most demanding tasks
Development of threshold strategy
Development of strength thresholds
Development of power thresholds
Development of endurance thresholds
Identification of most critical metric(s)

Ground based analogs with ambulatory subjects will be used to establish relationships between muscle performance metrics and tasks performance. Data mining from studies implementing muscle performance and functional task testing will also be used to improve models. Muscle performance thresholds (i.e. the fitness standards) will be established based on the relationships.

Target for Closure
Establishment of mission specific task requirements with muscle performance standards for each .  The most demanding task(s) for each mission can be used for setting thresholds, thus ensuring that nominal tasks can also be performed.
Risk Risk of Impaired Performance Due to Reduced Muscle Size, Strength and Endurance
You are here! Gap M4: Establish muscle function standards for successful completion of mission tasks.

Multi-Disciplinary Research Plans

No Documentation Available