Last Published:  07/31/19 10:05:30 AM (Central)
Responsible Element: Human Factors and Behavioral Performance (HFBP)
Status: Open

a)    Initial State

While it is necessary to determine the impact of environmental factors on sleep and performance, as well as the mission requirements that disrupt circadian rhythms and sleep, there are varied ways through which individuals respond to stressors. Recent studies have documented that there are large stable (trait-like) differences among individuals in the degree of cognitive deficits experienced during sleep loss. Identifying individual factors that mediate the degree to which an external stressor affects the individual will inform individual countermeasure recommendations.

b)    Target for Closure

(1) Identified behavioral and/or physiological marker(s) for individual vulnerabilities and resiliencies to sleep loss and circadian rhythm disruption based on the amount of variance seen in performance, across individuals in controlled experimental studies;
(2) Behavioral and/or physiological marker(s)  relationship to outcomes has been characterized;
(3) Guidelines for how these vulnerabilities and resiliencies can be used to define individual risk and  individualize countermeasure regimens.

c)    Metrics for Interim Progress

(1) Review status of what is known regarding behavioral and/or physiological marker(s) for individual vulnerabilities and sleep loss and circadian rhythm disruption, from spaceflight and ground studies (review completed 2010); update to include progress from military (5%);

(2) Assess potential collaborations within HRP, SD and externally (ONR?) (5%);

(3) Solicit and implement studies that evaluate performance relative to sleep duration, collecting data on individual behavioral and/or physiological marker(s) of interest (30%);

(3) With internal and external SMEs, develop methodology for using behavioral and/or physiological marker(s) as  individualized diagnostic and preventative countermeasure for mitigating sleep issues on autonomous, long duration and/or distance exploration missions (Sleep Gap 9 and Sleep Gap 10) (30%);

(4) Update as needed upon completion of research studies and as information about individual predictors and outcomes is defined (10%);

(5) Assess feasibility of incorporation into  sleep model  based on key behavioral and/or physiological marker(s) and quantified variances (Sleep Gap 8) (10%);

(6) Update flight rules, requirements, and clinical guidelines, as appropriate (per Sleep Gap 10) (10%).

d)    Approach

Progress has been made with evidence reports completed in 2009, current laboratory research through the NSBRI, and planned BHP research (Bmed) evaluating individuals in long duration isolation and confinement. Additionally, BHP researchers, through the support of other agencies, are evaluating genetic and other physiological pre-cursors to resiliencies and vulnerabilities. Data collected in analogs and spaceflight however need to be evaluated in light of sleep and circadian-related outcomes.

Target for Closure
No Target for Closure available.
Risk Risk of Performance Decrements and Adverse Health Outcomes Resulting from Sleep Loss, Circadian Desynchronization, and Work Overload
You are here! Gap Sleep Gap 4: We need to identify indicators of individual vulnerabilities and resiliencies to sleep loss and circadian rhythm disruption, to aid with individualized countermeasure regimens, for autonomous, long duration and/or distance exploration missions.

No Documentation Available