Gap Micro-301: Identify, develop, and implement in-flight microbial monitoring/diagnostic tools for support of research and crew health during Gateway, Lunar, and Mars missions.
Last Published:  07/30/21 01:05:31 PM (Central)
Responsible Element: Human Health Countermeasures (HHC)
Status: Open
Description
Present state of knowledge: The current space flight microbial requirements were developed for culture-based methodology, which is cumbersome and time-consuming and limits the types of technology that can be used for spaceflight monitoring. In addition, microbial identification currently requires sample return for processing on Earth, which will not be easily accomplished as spaceflight missions extend beyond low Earth orbit, due to the shelf life associated with consumables and limited down-mass capabilities. New requirements and associated advanced technologies need to be developed to enable in situ microbial identification that allows real-time information for risk assessment.
Research approach: HRP plans to fund studies via solicited and directed mechanisms, using flight and analog data, including but not limited to: 1) Identify, test in weightlessness, and modify “commercial off-the-shelf” (COTS) devices that can support microbial identification in-flight, and 2) Investigate alternative capabilities to determine virulence and antibiotic susceptibility. A portion of this work is under the purview of HRP’s Exploration Medical Capabilities (ExMC) Element, and inter-Element collaboration is expected for addressing this gap. Some of the work is also expected to occur under other NASA departments, such as ISS/ECLSS, SCLT, and AES.
Target for Closure
Validated microbial identification/diagnostic tools for in-mission use
Mappings
Risk Risk of Adverse Health Effects Due to Host-Microorganism Interactions
You are here! Gap Micro-301: Identify, develop, and implement in-flight microbial monitoring/diagnostic tools for support of research and crew health during Gateway, Lunar, and Mars missions.
Active
Completed
Planned-Funded

Multi-Disciplinary Research Plans

Documentation:
No Documentation Available