Short Title: Pharm Last Published:  11/23/20 11:55:09 AM (Central)
Element: Exploration Medical Capability (ExMC)
Evidence:  Report
Risk Master Logic Diagram:  Not Available
Point of Contact:  Kris Lehnhardt
HRP Risk Status: Active [current research ongoing]
Risk Ratings and Dispositions per Design Reference Mission (DRM) Category
DRM CategoriesMission
OperationsLong-Term Health
LxCRisk Disposition *LxCRisk Disposition *
Low Earth Orbit6 months1x1Accepted1x1Accepted
1 year1x1Accepted1x1Accepted
Deep Space Sortie1 month1x1Accepted1x1Accepted
Lunar Visit/
1 year1x1Accepted1x1Accepted
Deep Space
1 year2x2Accepted1x1Accepted
Planetary3 years3x4Requires Mitigation3x4Requires Mitigation
Note: LxC is the likelihood and consequence rating. The information above was last approved by the Human System Risk Board in 5/2019.
Risk Statement
Given that there is no current method to sufficiently characterize medication use, drug quality and performance, clinical outcomes, and the impact of a hostile space environment on pharmaceutical stability and potency during long-duration exploration missions, there is a possibility that provision of a safe and effective drug treatment will be significantly limited, impacting crew health and performance.
Gaps (6)