Funding Status:
Completed - Task completed and produced a deliverable
Procurement Mechanism(s):
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Aims:
This proposal aims to validate in an analog setting a small compact exercise device for the
protection of cardiovascular, muscle, and bone health. This study leverages both currently funded
NSRBRI and NASA work to bring together for the first time, a promising new exercise device and
exercise prescription thus placing this study at a high countermeasure readiness level (moving
from 6-7). More specifically, the NSBRI funded M-MED device uses a flywheel to provide loading for
either high force-low repetition resistance exercise or low force-high repetition, endurance exercise
(rowing). Recent data support M-MED training effectiveness in both ambulatory subjects and over
10 days of muscle unloading using unilateral lower limb suspension model. Accordingly, a new
NASA funded exercise prescription study integrating resistance and aerobic training (iRAT) has
been effective in the preservation of muscle and cardiovascular function over 14 days of bedrest,
but requires the use of 5 different exercise machines. This proposal will combine the M-MED
exercise device and the iRAT exercise prescription into a 70 day bedrest study. Outcome
measurements related to cardiovascular, muscle and bone health will be obtained and integrated to
assess countermeasure effectiveness.
Integration/Unique Aspects: Task to start 10/1/2012.