HRR - Task - Mathematical Modeling of Circadian/Performance Countermeasures

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Mathematical Modeling of Circadian/Performance Countermeasures (Completed)

Last Published: 07/31/19 10:05:33 AM (Central)

Task Book: Entry
Principal Investigator: Klerman, Elizabeth

Short Title: CPSS Modeling Harvard

Responsible HRP Element: Behavioral Health and Performance

Collaborating Org(s):

National Space Biomedical Research Institute (NSBRI)

Other:

Funding Status: Completed - Task completed and produced a deliverable

Procurement Mechanism(s):

Solicited

Aims:

Specific Aim 1: Develop and refine the current circadian, neurobehavioral performance and subjective alertness (CNPA) model with melatonin as a marker rhythm to accurately predict phase and amplitude of the circadian pacemaker.

Specific Aim 2: Refine and validate the current model by using data from chronic sleep restriction protocols.

Specific Aim 3: Refine the current model to incorporate wavelength of light information.

Specific Aim 4: Develop Schedule Assessment and Countermeasure Design Software using the amended CPNA model from Specific Aims 1, 2 and 3 to evaluate schedules and design and test appropriate countermeasures.

Resources (None Listed)

Deliverables (1)