Task A Model of Circadian Disruption in the Space Environment (Completed)
Last Published:  07/29/22 01:33:24 PM (Central)
Short Title: Circadian Disruption
Responsible HRP Element: Behavioral Health and Performance
Collaborating Org(s):
National Space Biomedical Research Institute (NSBRI)
Funding Status: Completed - Task completed and produced a deliverable
Procurement Mechanism(s):

SPECIFIC AIM I: Using rhythms of gene expression reported by a luciferase transgene, we will identify the signals linking brain and peripheral oscillators.

SPECIFIC AIM II: We will evaluate potential countermeasures by exposing our experimental animals to conditions that disrupt the normal circadian phase map and then determining if the potential countermeasures are able to restore it rapidly.

SPECIFIC AIM III: Investigate the effects of chronic low dose methamphetamine in synchronizing disrupted rhythms and evaluate related drugs as potential countermeasures.

Resources (None Listed)