Task A Scanning Confocal Acoustic Diagnostic System for Non-Invasively Assessing Bone Quality (Completed)
Last Published:  03/29/18 08:54:56 AM (Central)
Short Title: Acoustic Bone Quality
Responsible HRP Element: Human Health Countermeasures
Collaborating Org(s):
Funding Status: Completed - Task completed and produced a deliverable
Procurement Mechanism(s):

1: Developed a rapid scanning confocal acoustic diagnostic (SCAD) system capable of generating high-resolution acoustic images for trabecular structural and strength properties in the region of interest (ROI).

2: Developed the system capable of extracting trabecular broadband ultrasound attenuation (BUA) and UV images at multiple skeletal sites, i.e., calcaneus, wrist, and knee, providing evaluation of loss and fracture risk.

3: Evaluated the capability of the SCAD system in testing bone's structure and strength in cadavers by micro-CT determined microstructure, nanoindentor tested integrity, and modulus.

4: Correlated the degree of osteoporosis and disuse osteopenia in human to determine the relationship to age, gender, degree of bone loss and rational effects at ROI using SCAD and DXA.

Resources (None Listed)