Task High LET-radiation induced DNA repair mechanisms in Oligodendrocyte progenitor cells (OPC) in vitro and in vivo - CCSB (Completed)
Last Published:  07/31/19 10:05:33 AM (Central)
Short Title: OPC II
Responsible HRP Element: Space Radiation
Collaborating Org(s):
Other:
Funding Status: Completed - Task completed and produced a deliverable
Procurement Mechanism(s):
Solicited
Aims:

 

Determine the effects of high LET radiation on the nuclear and mitochondrial BER in two systems:
  1. the central glia-4 (CG-4), a glial progenitor cell line that can differentiate into OL or astrocytes, and
  2. In OPC cells isolated from rat spinal cord.
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