Task Effects of Angiotensin Converting Enzyme Inhibitors on Bone Turnover (Completed)
Last Published:  07/30/21 01:05:34 PM (Central)
Short Title: Bone Turnover Markers-Rianon
Responsible HRP Element: Human Health Countermeasures
Collaborating Org(s):
Funding Status: Completed - Task completed and produced a deliverable
Procurement Mechanism(s):
Solicited
Aims:

Among subjects (men and women ≥ 45 years of age) with hypertension and no known history of osteoporosis attending outpatient clinics:

1) To compare changes in bone turnover markers (P1NP and CTX) between randomized groups with and without exposure to ACEI for 3 months

2) To compare changes in serum levels of RANKL protein between randomized groups with and without exposure to ACEI for 3 months.

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