Short Title:
LSMMG Probiotic
Responsible HRP Element:
Space Human Factors and Habitability
Funding Status:
Completed - Task completed and produced a deliverable
Procurement Mechanism(s):
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Aims:
Determine the effects of LSMMG culture on the growth, stress response, and transcriptomic profile of L. acidophilus ATCC 4356.
Will contribute to AEH and Immune.
Category:
Countermeasure
Subcategory:
Clinical Procedure/Prescription
Description:
The final deliverable was a report that showed evidence that LSMMG culture does not impact the growth, stress response, and gene expression of L. acidophilus. The deliverable contributed to gap closure and risk mitigation by characterizing a probiotic's response to a spaceflight analogue environment, indicating that for this probiotic characteristics are consistent with Earth-based culture and benefits may be expected to transfer to spaceflight. Investigation of more strains in future would define strain selection criteria for spaceflight.
Internal Customers:
Space Human Factors and Habitability
External Customers:
None