Task Molecular characterization of transmissible chromosome aberrations produced by ions of intermediate and high atomic number (Completed)
Last Published:  07/29/22 01:33:24 PM (Central)
Short Title: Chromosome Aberrations
Responsible HRP Element: Space Radiation
Collaborating Org(s):
Funding Status: Completed - Task completed and produced a deliverable
Procurement Mechanism(s):

Objective 1: Isolate progeny (clones) of irradiated single cells and analyze for the presence of transmissible chromosome aberrations

Objective 2:
Next generation sequencing approaches will be employed to characterize, at the DNA level, the nature of breakpoint junctions of the chromosome translocations and inversions identified in Objective 1.

Objective 3: Examine cytogenetic Effects of Abrogating CtIP activity.
Resources (None Listed)