Task Functional Immune -DNA damage in the ISS astronaut's lymphocytes and their association with stress-induced immune dysfunction (Honglu Wu) Functional immune
Last Published:  07/30/21 01:05:34 PM (Central)
Short Title: Functional Immune - DNA damage
Responsible HRP Element: Human Health Countermeasures
Collaborating Org(s):
Human Health Countermeasures (HHC) Element
Funding Status: Active - Currently funded and in progress
Procurement Mechanism(s):
Solicited
Aims:

[A] Determine the in-flight status of immune dysregulation (innate + adaptive) in conjunction with relevant parameters from other disciplines (nutrition, radiation, virology, host-pathogen, stress, etc.).

[B] Determine the post-flight time course to full recover for dysregulated parameters.

[C] Derive a final refined monitoring strategy encompassing innate immunity, adaptive immunity and relevant parameters from other disciplines which will be appropriate to validate countermeasures.


Integration/Unique Aspects: TBD,  functional immune is a hybrid study that incorporates a directed portion with solicited portions.


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