Last Published:  03/26/21 03:34:00 PM (Central)
Short Title: Inter-Agency MCM Studies
Responsible HRP Element: Space Radiation
Collaborating Org(s):
Funding Status: Planned-Funded - Task expected to be within budget
Procurement Mechanism(s):
Directed
Aims:

Specific Aims:

  • Aim 1: Identify and prioritize candidate radioprotective and chemopreventive agents to mitigate radiation health risks

  • Aim 2: Perform preliminary countermeasure evaluation using radioprotective/chemopreventive agents that target common pathways of radiation induced injury (e.g. inflammation).

  • Aim 3: Test efficacy of selected medical countermeasures in space relevant environments.


Resources (None Listed)
Mappings
RiskRisk of Acute (In-flight) and Late Central Nervous System Effects from Radiation Exposure
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RiskRisk of Adverse Cognitive or Behavioral Conditions and Psychiatric Disorders
GapBMed-103: What are the validated, efficacious treatments (individual or Team-based) and/or countermeasures to prevent adverse behavioral conditions, CNS/neurological, and/or psychiatric disorders caused by either single and/or integrated exposures to spaceflight hazards during exploration class missions?
GapBMed-104: Given the potentially negative spaceflight associated CNS changes and behavioral experiences of stressors during long-duration missions (e.g., isolation, confinement, reduced sensory stimulation, altered gravity, space radiation), what are validated modifications to habitat/vehicle to mitigate stressors impacting on CNS / cognition / behavioral health?
GapBMed-105: Given the potentially negative spaceflight associated CNS/cognitive changes and behavioral experiences of stressors during long-duration missions (e.g., isolation, confinement, reduced sensory stimulation, altered gravity, space radiation), what are validated medical or dietary countermeasures to mitigate stressors impacting on CNS / cognition / behavioral health?
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RiskRisk of Cardiovascular Disease and Other Degenerative Tissue Effects From Radiation Exposure and Secondary Spaceflight Stressors
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RiskRisk of Radiation Carcinogenesis
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RiskRisk of Spaceflight Induced Cardiovascular Disease
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