Last Published:  07/31/19 10:05:33 AM (Central)
Short Title: CBS Operational Performance Measures (Roma)
Responsible HRP Element: Human Factors and Behavioral Performance
Collaborating Org(s):
Human Health Countermeasures (HHC) Element
Other:
Space Radiation (SR) Element
Funding Status: Active - Currently funded and in progress
Procurement Mechanism(s):
Directed
Aims:
Identification and integration of operationally-relevant performance tasks from available performance measures across disciplines to determine necessary and sufficient performance measures for use in future research (working group). Scope of this effort is to identify the BHP Ops relevant performance measures and link these to Brain Performance Pathways for use by Translational Modeling efforts.
Aim 1. Thorough review of NASA technical and internal documents and the scientific literature and input from NASA Operations experts, identify the core tasks, individual and team performance abilities, and behavioral health and performance competencies for long-duration space exploration missions.
Aim 2. Thorough review of the CNS/SM/BMed scientific literature and NASA technical and internal documents, identify the constituent neurobehavioral processes (e.g., attention, short-term memory, verbal communication), Brain Performance Pathways, and neurobehavioral, neuroanatomical, and neurochemical substrates underlying each of the core tasks, individual and team performance abilities, and behavioral health and performance competencies for long-duration space exploration missions identified in Aim 1.
Aim 3. Thorough review of the CNS/SM/BMed scientific literature and NASA technical and internal documents, identify and assess the sensitivity, reliability, validity, translational potential, and redundancy of existing research measures of the constituent neurobehavioral processes, Brain Performance Pathways, and neurobehavioral, neuroanatomical, and neurochemical substrates underlying the core tasks, individual and team performance abilities, and behavioral health and performance competencies for long-duration space exploration missions identified in Aim 2.
Aim 4. Integrate the results of Aims 1-3 into a spreadsheet summarizing the findings and allowing for identification of relative strengths and weaknesses of each potential operational performance measure and potential redundancy of measures via overlapping Brain Performance Pathways.
Aim 5. If available, incorporate into the summary spreadsheet created in Aim 4 the results of other CBS Operational Performance Measures and CBS integrated datamining Directed Tasks.  This may include, but is not limited to, CBS Data Mining (PI A. Mulavara), CBS NHP CNS Radiation/Performance Data Mining (PI TBD), and CBS RR: Neurobehavioral Biomarkers Performance/Pathway (PI TBD).
Aim 6. Draft a report summarizing the project, including rationale/background, methodology, results, and discussion.  Recommend to NASA an evidence-based set(s) of candidate operationally-relevant Brain Performance Pathways measures applicable across multiple Risk areas for use in an integrated, translational CNS/BMed/SM research plan.
Resources (None Listed)
Mappings
RiskRisk of Acute (In-flight) and Late Central Nervous System Effects from Radiation Exposure
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RiskRisk of Adverse Cognitive or Behavioral Conditions and Psychiatric Disorders
GapCBS-BMed2: We need to identify and validate measures to monitor behavioral health and performance during exploration class missions to determine acceptable thresholds for these measures.
GapCBS-CNS - 1: Are there significant adverse changes in CNS performance in the context and time scale of spaceflight operations? If so, how is significance defined, and which neuropsychological domains are affected? Is there a significant probability that space radiation exposure would result in adverse changes? What are the pathways and mechanisms of change?
GapCBS-CNS - 8: Are there significant CNS risks from combined space radiation and other physiological or space flight factors, e.g., psychological (isolation and confinement), altered gravity (micro-gravity), stress, sleep deficiency, altered circadian rhythms, hypercapnea, altered immune, endocrine and metabolic function, or other?
GapCBS-SM2.1: Determine the changes in sensorimotor function over the course of a mission and during recovery after landing.
GapCBS-SM26: Determine if exposure to long-duration spaceflight leads to neural structural alterations and if this remodeling impacts cognitive and functional performance.
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RiskRisk of Impaired Control of Spacecraft/Associated Systems and Decreased Mobility Due to Vestibular/Sensorimotor Alterations Associated with Spaceflight
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RiskRisk of Inadequate Mission, Process and Task Design
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RiskRisk of Performance and Behavioral Health Decrements Due to Inadequate Cooperation, Coordination, Communication, and Psychosocial Adaptation within a Team
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RiskRisk of Performance Errors Due to Training Deficiencies
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