Task Alterations in Energy Metabolism Pathways in Skeletal Muscle in Relation to Microgravity Analog and Space Radiation
Last Published:  07/30/21 01:05:34 PM (Central)
Short Title: Metabolism Pathways in Skeletal Muscle
Responsible HRP Element: Human Health Countermeasures
Collaborating Org(s):
Funding Status: Active - Currently funded and in progress
Procurement Mechanism(s):
Solicited
Aims:

Aim 1: Identify metabolic perturbations in gastrocnemius and quadricep muscles through

metabolomics relating to space radiation and/or the μG analog HU, with focus on energy and

mitochondrial related pathways.

Aim 2: Determine whether the combined effects of radiation and HU exhibit an additive or

synergistic effect in metabolic pathways, with emphasis on cofactors that can be explored as

countermeasures.


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