Short Title:
Vitamin D Dosing
Responsible HRP Element:
Human Health Countermeasures
Funding Status:
Completed - Task completed and produced a deliverable
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Procurement Mechanism(s):
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Aims:
- Determine the time course and magnitude of changes in vitamin D and vitamin D metabolite status with each dose of vitamin D supplementation. We will also determine markers of calcium and liver enzyme status to document potential side effects.
- Determine other markers of bone and calcium metabolism (including serum and urinary calcium, bone-specific alkaline phosphatase, 1,25-dihydroxyvitamin D, parathyroid hormone, and vitamin D binding protein) and vitamin D metabolites over a 4-month course of vitamin D supplementation, to determine the effectiveness and safety of each level of supplementation.
Integration/Unique Aspects: TBD
Category:
Risk Characterization, Quantification
Subcategory:
Evidence or Risk Characterization
Description:
Report
Internal Customers:
Human Health Countermeasures
External Customers:
None