Task Identification of cardiometabolic vulnerabilities caused by effects of synergistic stressors that are commonly encountered during space missions (Cardiometabolic Vulnerabilities-Shea, Active) (Completed)
Last Published:  07/31/19 10:05:33 AM (Central)
Short Title: Cardiometabolic Vulnerabilities
Responsible HRP Element: Human Health Countermeasures
Collaborating Org(s):
Human Health Countermeasures (HHC) Element
Other:
Funding Status: Completed - Task completed and produced a deliverable
Procurement Mechanism(s):
Solicited
Aims:
Under extremely physiological challenging circumstances, i.e. microgravity, astronauts are expected to perform tasks that add additional physical and mental stress to their cardiovascular system such as space walks or robotic operations during EVAs. To date we know little to nothing about the synergetic effects of chronic sleep restriction, circadian misalignment, and physical and mental stressors on cardiovascular functioning.
The main aims of this four year NASA project are:
  1. To characterize the alterations (and potential maladaptations) of cardiovascular and cardiometabolic function (i.e. hemodynamic, haemostatic, autonomous nervous functioning, cardiac vulnerability, energy metabolism) associated with chronic sleep restriction and circadian misalignment occurring during short and long term duration space missions (e.g. Lunar sortie, Lunar outpost, and mission to Mars);
  2. To characterize the effects of different types of stressors (postural, exercise, and mental stressors; except microgravity) on cardiovascular and cardiometabolic functioning during short and long term duration space missions; and
  3. To identify the synergetic effects of chronic sleep restriction, circadian misalignment, and different stressors, potentially identifying in vulnerable periods with an increased likelihood of adverse cardiac events during short and long term duration space missions.
Mappings
RiskRisk of Adverse Cognitive or Behavioral Conditions and Psychiatric Disorders
You are here!TaskIdentification of cardiometabolic vulnerabilities caused by effects of synergistic stressors that are commonly encountered during space missions (Cardiometabolic Vulnerabilities-Shea, Active)

RiskRisk of Adverse Health Event Due to Altered Immune Response
You are here!TaskIdentification of cardiometabolic vulnerabilities caused by effects of synergistic stressors that are commonly encountered during space missions (Cardiometabolic Vulnerabilities-Shea, Active)

RiskRisk of Cardiac Rhythm Problems
You are here!TaskIdentification of cardiometabolic vulnerabilities caused by effects of synergistic stressors that are commonly encountered during space missions (Cardiometabolic Vulnerabilities-Shea, Active)