Short Title:
Telomere dysfunction
Responsible HRP Element:
Space Radiation
Funding Status:
Completed - Task completed and produced a deliverable
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Procurement Mechanism(s):
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Aims:
This research project will explore the effects of radiation quality on the dose-response relationship for telomere aberrations and gene mutations in human cells. It will relate these two potential cancer development processes by determining whether telomere-double strand break fusions are a significant contributor to the overall mutagenic response of a cell to ionizing radiation. Finally, it will explore various aspects of radiation-induced bystander effects, where cells not directly traversed by ionizing radiation nevertheless exhibit genetic damage.
Category:
Risk Characterization, Quantification
Subcategory:
Evidence or Risk Characterization
Description:
Annual Report
Internal Customers:
None
External Customers:
None
Category:
Risk Characterization, Quantification
Subcategory:
Evidence or Risk Characterization
Description:
Annual Report
Internal Customers:
None
External Customers:
None
Category:
Risk Characterization, Quantification
Subcategory:
Evidence or Risk Characterization
Description:
Final Report
Internal Customers:
None
External Customers:
None