1 .The data related to the risk of renal stone formation (medical data and raw research data used for published reports) should be shared with the Bone Team as part of a comprehensive, Bone Epidemiology Analysis of Astronaut Flight Medical Data.

2. Stone formation in the post-flight period should continue to be monitored in order to expand the data-to-date, particularly with regards to the types of stones formed (to identify the specific risk factor and appropriate countermeasure), the correlation with diet and the time course for formation.

1. Quantitate the pre- in- and postflight risk of renal stone formation associated with space flight. 
2. Determine the efficacy of potassium citrate as a countermeasure in reducing the in-flight and postflight for renal stone formation.
3. Evaluate dietary impact on the urinary biochemistry.
4. Evaluate the potential benefit of citrate to inhibit bone loss.