Last Published:  07/30/21 01:05:31 PM (Central)
Responsible Element: Human Health Countermeasures (HHC)
Status: Open

Initial State of Gap: Post-flight orthostatic intolerance, the inability to maintain blood pressure while in an upright position, is an established, spaceflight-related medical problem. Risk definition work was largely accomplished prior to establishment of HRP risks/gaps.  Current gaps are heavily focused on mitigation.  Countermeasures have been identified and implemented with some success (fluid loading, compression garments). A customized gradient compression garment is in the verification stage for long/exploration spaceflight. It is currently unknown if partial gravity (moon, Mars) will be protective against OI.

Target for Gap Closure: Provide a verified design for customized gradient compression garments and protocol for implementation.

Approach: Complete current and planned improved fluid loading ground and flight studies to determine if the current fluid loading protocol can be enhanced. Complete studies to evaluate the effectiveness of the gradient compression garment after long-duration (> 3 months) space flight to optimize countermeasure.

Target for Closure
No Target for Closure available.
You are here! Gap CV3: Is orthostatic intolerance a potential hazard?

Multi-Disciplinary Research Plans

No Documentation Available