HRR - Gap - MICRO-04: We need to determine how physical stimuli specific to the spaceflight environment, such as microgravity, induce unique changes in the dose-response profiles of expected medically significant microorganisms. (Previous title: AEH 14)

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MICRO-04: We need to determine how physical stimuli specific to the spaceflight environment, such as microgravity, induce unique changes in the dose-response profiles of expected medically significant microorganisms. (Previous title: AEH 14)

This Gap was split into the following Gaps:

Micro-201: Evaluate the contribution of changes in microbial numbers, types, and virulence on the likelihood and consequence of adverse health events (infection and allergic response), during the mission.

Micro-101: Evaluate the effects of isolation, confinement and weightlessness on changes in the vehicle microbiome, the human microbiome, and microbial virulence.

Micro-103: Evaluate whether atmospheric composition (for example, elevated CO2 levels) is a significant contributor to changes in the microbial profile of spaceflight.

Micro-102: Evaluate whether deep-space radiation has an additive or synergistic effect with weightlessness/isolation/confinement on microbial types, numbers, and virulence.

Split Rationale

No rationale available.

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