Gap Pharm-101: We need to determine the optimal packaging/storage strategy for medications in space that balances the needs of mitigating toxicity, preserving effectiveness, and minimizing resource “costs” (mass, volume, power, etc.).
Last Published:  07/30/21 01:05:31 PM (Central)
Responsible Element: Exploration Medical Capability (ExMC)
Status: Open
Description

State of Knowledge: Medications have been shown to change in the space environment. The exact mechanisms have not been delineated but contributing factors may include radiation exposure and ambient environmental conditions.  Many medications on the International Space Station are repackaged from initial manufacturers’ packaging for operational reasons (mass/volume reductions, convenience of use) and it is unclear if this approach exacerbates the changes seen in the space environment.

Approach: We will consider a variety of packaging and storage solutions, including but not limited to: keeping all medications in manufacturers’ packaging; re-packaging medications using current operational parameters; novel packaging/storage options; and environmental control chambers and/or shielding.  For each of these solutions, analysis shall consider the following components: benefits with respect to preserving effectiveness and minimizing toxicity; resource “costs” associated with solution (mass, volume, power, etc.); and operational impacts including pre-flight packaging implications (timing, location, storage, etc.) and techniques/technologies necessary for novel packaging solution.

Target for Closure

Recommendation of packaging/storage strategies to be incorporated into future exploration spaceflight operations

Mappings
Risk Risk of Ineffective or Toxic Medications During Long-Duration Exploration Spaceflight
You are here! Gap Pharm-101: We need to determine the optimal packaging/storage strategy for medications in space that balances the needs of mitigating toxicity, preserving effectiveness, and minimizing resource “costs” (mass, volume, power, etc.).
Completed
Planned-Funded

Multi-Disciplinary Research Plans

Documentation:
No Documentation Available