Gap Pharm-301: We need to categorize all medications that are included in the iterative Exploration Candidate Formulary based upon the current state of knowledge of their effectiveness and safety in the spaceflight environment.
Last Published:  07/30/21 01:05:31 PM (Central)
Responsible Element: Exploration Medical Capability (ExMC)
Status: Open
Description

State of Knowledge: Insufficient information has previously been gathered on the extent to which medications change in the spaceflight environment. Furthermore, there are a number of potential factors that may contribute to the overall safety and effectiveness profile of any given medication considered for exploration spaceflight and the relative contribution of each of these factors is unclear. It is believed that there is additional existing evidence available that must be gathered and collated for each medication being considered for the Exploration Candidate Formulary.

Approach: The initial effort will be to synthesize all known ground, analog, and spaceflight data from all available sources (including NASA, academia, pharmaceutical companies, and other governmental organizations) for each medication on the iterative Exploration Candidate Formulary with respect to safety and effectiveness. This data will be used to feed a systematic process whereby each medication on the Exploration Candidate Formulary will then be categorized in terms of the level of confidence that sufficient information is currently available to accurately predict each medication’s safety and effectiveness profile for exploration missions.

Target for Closure
1.Accepted systematic process for medication safety and effectiveness categorization

2.Application of accepted categorization process for all medications on the iterative Exploration Candidate Formulary
Mappings
Risk Risk of Ineffective or Toxic Medications During Long-Duration Exploration Spaceflight
You are here! Gap Pharm-301: We need to categorize all medications that are included in the iterative Exploration Candidate Formulary based upon the current state of knowledge of their effectiveness and safety in the spaceflight environment.
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Multi-Disciplinary Research Plans

Documentation:
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