Gap CVD-301: Test the integrated countermeasure suite in deep-space missions and on the moon, based on previous tests of countermeasures on the ground and ISS.
Last Published:  07/30/21 01:05:31 PM (Central)
Responsible Element: Human Health Countermeasures (HHC)
Status: Open
Description
Present state of knowledge: Only the Apollo astronauts have traveled beyond the protection of van Allen Belts and been subjected to the combined effects of weightlessness and exposure to deep space radiation. No specific countermeasures were tested beyond the provision of radiation shielding, limiting exposure time, and a small exercise device. Based upon ground-based data in ambulatory subjects, including those who received radiation therapy, countermeasures might include maintenance of appropriate habits during the mission (e.g., exercise, appropriate dietary choices, improved sleep habits, managing psychological stress) as well as administration of dietary or pharmacological interventions such as sulfhydryl or thiol compounds, anti-oxidants, anti-inflammatories, and cholesterol level-modifying medications (e.g., statins and γ-tocotrienol).

Research approach: Data collection on astronauts during various Gateway and Lunar missions using the suggested countermeasures.
Target for Closure
An operationally viable cardiovascular countermeasure suite against the negative health effects of deep-space missions.
Mappings
Risk Risk of Cardiovascular Adaptations Contributing to Adverse Mission Performance and Health Outcomes
You are here! Gap CVD-301: Test the integrated countermeasure suite in deep-space missions and on the moon, based on previous tests of countermeasures on the ground and ISS.
Planned-Funded

Multi-Disciplinary Research Plans

Documentation:
No Documentation Available