Risk Risk of Adverse Health Event Due to Altered Immune Response
Short Title: Immune Last Published:  04/26/21 11:19:46 AM (Central)
Element: Human Health Countermeasures (HHC)
Evidence:  Report
Risk Master Logic Diagram:  Diagram
Point of Contact:  Brian Crucian
HRP Risk Status: Active [current research ongoing]
Risk Ratings and Dispositions per Design Reference Mission (DRM) Category
DRM CategoriesMission Type and
Duration
OperationsLong-Term Health
LxCRisk Disposition *LxCRisk Disposition *
Low Earth OrbitShort
(<30 days)
3x2Accepted with Monitoring3x1Accepted with Monitoring
Long
(30 days-1 year)
3x2Accepted with Monitoring3x1Accepted with Monitoring
Lunar OrbitalShort
(<30 days)
3x2Accepted with Monitoring3x1Accepted with Monitoring
Long
(30 days-1 year)
3x2Accepted with Monitoring3x1Accepted with Monitoring
Lunar Orbital
+ Surface
Short
(<30 days)
3x2Accepted with Monitoring3x1Accepted with Monitoring
Long
(30 days-1 year)
3x2Requires Mitigation3x2Requires Mitigation
MarsPreparatory
(<1 year)
3x3Requires Mitigation3x2Requires Characterization
Mars Planetary
(730-1224 days)
3x3Requires Mitigation3x2Requires Characterization
Note: LxC is the likelihood and consequence rating. The information above was last approved by the Human System Risk Board in 12/2020.
Risk Statement
Given that exposure to orbital spaceflight results in persistent dysregulation of the immune system, which leads to reactivation of latent herpes-viruses and likely to an increased clinical incidence, including rashes and hypersensitivity reactions, there is a possibility that certain diseases will occur during exploration class missions.
Gaps (12)