Task Simulated space radiation and weightlessness: vascular-bone coupling mechanisms to preserve skeletal health (Completed)
Last Published:  07/29/22 01:33:24 PM (Central)
Short Title: Vascular-bone Coupling and Skeletal Health
Responsible HRP Element: Human Health Countermeasures
Collaborating Org(s):
National Space Biomedical Research Institute (NSBRI)
Funding Status: Completed - Task completed and produced a deliverable
Procurement Mechanism(s):
  1. Determine the functional and structural consequences of prolonged weightlessness and space radiation (simulated spaceflight) for bone and skeletal vasculature in the context of bone cell function and oxidative stress.
  2. Determine the extent to which an anti-oxidant protects against weightlessness and space radiation-induced bone loss and vascular dysfunction.
  3. Determine how space radiation influences later skeletal and vascular recovery from prolonged weightlessness and the potential of anti-oxidants to improve or prevent this recovery.