Task Targeting protein cross talk signaling as a biological predictor for space radiation cancer risk (Completed)
Last Published:  11/23/20 11:55:12 AM (Central)
Short Title: Protein Cross Talk
Responsible HRP Element: Space Radiation
Collaborating Org(s):
Funding Status: Completed - Task completed and produced a deliverable
Procurement Mechanism(s):
Solicited
Aims:
In this project we address:
  1. How low doses of high LET radiation trigger initial damage signals that remain persistent and are maintained in the memory of the cell/tissue,
  2. How these signals are amplified,
  3. How these amplified signals are transmitted to result in a sustained radial expansion of initial damage, and finally
  4. How radial communication of these signals activates factors that are responsible for predisposing the susceptible cells to carcinogenesis.
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