Short Title:
Bone Exercise CM
Responsible HRP Element:
Human Health Countermeasures
|
Collaborating Org(s):
|
| National Space Biomedical Research Institute (NSBRI) |
|
Funding Status:
Completed - Task completed and produced a deliverable
|
Procurement Mechanism(s):
|
|
Aims:
- Test two different modes of resistance training
(electrically stimulated muscle contractions versus voluntary resistance
exercise) for their effects on mitigating bone and muscle decrements
during 28 days of hindlimb unloading (HU) in adult rats.
- Test different doses of alendronate during 28 days HU for maximal efficacy in suppressing bone resorption.
- Combine alendronate with that training paradigm judged most successful to test for additive or synergistic effects.
Category:
Risk Characterization, Quantification
Subcategory:
Evidence or Risk Characterization
Description:
Report
Internal Customers:
None
External Customers:
None