Task Comparative Analysis of Fe-Induced Autosomal Mutations in Murine Tissue and Cell Lines (Completed)
Last Published:  11/23/20 11:55:12 AM (Central)
Short Title: Autosomal Mutation
Responsible HRP Element: Space Radiation
Collaborating Org(s):
Funding Status: Completed - Task completed and produced a deliverable
Procurement Mechanism(s):
Solicited
Aims:
The goal of this study is to determine whether the tissue microenvironment modifies the mutagenic response of epithelial cells to charged particle radiation of importance in spaceflight. Mutant frequencies and mutant spectra will be evaluated in isogenic kidney epithelial cells exposed either in vitro or in vivo.
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