Task The Contribution of Tissue Level Organization to Genomic Stability Following Low Dose/Low Dose Rate Gamma and Proton Irradiation (Completed)
Last Published:  03/26/21 03:34:00 PM (Central)
Short Title: Tissue Organization
Responsible HRP Element: Space Radiation
Collaborating Org(s):
Department of Energy (DoE)
Funding Status: Completed - Task completed and produced a deliverable
Procurement Mechanism(s):

Our study proposes that the level of tissue organization will affect the induction and persistence of low dose radiation-induced genomic instability. To investigate this hypothesis we are using rat thyroid cells grown in vitro as three-dimensional (3D) tissue analogs in bioreactors and as traditional two-dimensional (2D) flask grown cultures.

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