Funding Status:
Completed - Task completed and produced a deliverable
Procurement Mechanism(s):
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Aims:
The specific aims of the study
were:
1) to determine effects of
maintenance of female subjects in the head-down tilt bed-rest model on
functional immune responses. This will be determined by examining the effects
of bed-rest on immunization to the innocuous bacteriophage PhiX-174, and on
leukocyte proliferation and cytokine production.
2) to determine effects of maintenance of female subjects in the head-down tilt
bed-rest model on resistance to infection. This will be determined by examining
the effects of bed rest on reactivation of persistent virus infections with
which the subjects are already infected, including Epstein-Barr virus and human
polyomaviruses.
Integration/Unique Aspects: unknown