Task Functional Role Of The Betaig-H3 Gene In High-Energy Heavy Ions-Induced Carcinogenesis (Completed)
Last Published:  11/23/20 11:55:12 AM (Central)
Short Title: Betaig
Responsible HRP Element: Space Radiation
Collaborating Org(s):
Space Biology Program
Funding Status: Completed - Task completed and produced a deliverable
Procurement Mechanism(s):
Solicited
Aims:
  1. To establish the tumorigenic cell model by irradiating hTERT-SAEC cells using beams of charged heavy ions;
  2. To demonstrate that loss of Betaig-h3 expression is causally related to the malignant transformation process; and
  3. To generate mouse embryonic stem cells and knock-out mice with disrupted Betaig-h3 gene.
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