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Task Stability of Pharmacotherapeutics and Nutrition Compounds-Pharm (Completed)
Last Published:  07/29/22 01:33:24 PM (Central)
Task Book: Entry
Principal Investigator: Putcha, Lakshmi
Short Title: Stability SMO - Pharm
Responsible HRP Element: Human Health Countermeasures
Collaborating Org(s):
Funding Status: Completed - Task completed and produced a deliverable
Procurement Mechanism(s):
Solicited
Aims:
The study aim was to determine the effects of space flight aging on medication stability.This study was inconclusive. But did provide one publication  by Du et al. (2010)
Resources (None Listed)
Mappings
RiskRisk of Ineffective or Toxic Medications During Long-Duration Exploration Spaceflight
GapPharm-101: We need to determine the optimal packaging/storage strategy for medications in space that balances the needs of mitigating toxicity, preserving effectiveness, and minimizing resource “costs” (mass, volume, power, etc.).
GapPharm-201: We need to establish an exploration formulary that identifies medications with maximal clinical benefit and minimal resource “costs” (mass, volume, etc.).
GapPharm-301: We need to categorize all medications that are included in the iterative Exploration Candidate Formulary based upon the current state of knowledge of their effectiveness and safety in the spaceflight environment.
GapPharm-401: We need to perform further research to understand and characterize the active pharmaceutical ingredient and degradation profiles of medications for which we have low to moderate confidence in their safety and effectiveness for exploration missions.
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Risk Approach Plans (1)