Task Inflight pharmacokinetic and pharmacodynamic responses to medications commonly used in spaceflight
Last Published:  07/31/19 10:05:33 AM (Central)
Short Title: Rx Metabolism
Responsible HRP Element: Human Health Countermeasures
Collaborating Org(s):
Human Health Countermeasures (HHC) Element
Funding Status: Terminated - A formerly active task that was stopped before its completion date due to deselection, descoping, reorganization etc.
Procurement Mechanism(s):
1. Determine PK for two medications groups frequently used by crewmembers in two different environments: on Earth and during a spcaeflight mission.
2. Determine spaceflight vs ground differences in medication associated effects on sleep wakefulness, and several measures of cognitive function as measures of pharmocodynamics (PD).

Integration/Unique Aspects: Will inform all disciplines and Space Medicine.