HRR - Task - Analysis of a Clinical Database as a Means to Validate Non-invasive Assessment of Intracranial Pressure Using the Cerebral and Cochlear Fluid Pressure (CCFP) Analyzer [CCFP DATA MINING/EBERT/COMPLETED]

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Analysis of a Clinical Database as a Means to Validate Non-invasive Assessment of Intracranial Pressure Using the Cerebral and Cochlear Fluid Pressure (CCFP) Analyzer [CCFP DATA MINING/EBERT/COMPLETED] (Completed)

Last Published: 07/30/21 01:05:34 PM (Central)

Task Book: Entry Unavailable
Principal Investigator: Ebert, Doug

Short Title: CCFP Data Mining

Responsible HRP Element: Human Health Countermeasures

Collaborating Org(s):

Space Medicine Medical Operations (SMMO)

Funding Status: Completed - Task completed and produced a deliverable

Procurement Mechanism(s):

Directed

Aims:
1. Correlate tympanic membrane displacement (TMD) analysis with lumbar puncture (LP) data in a retrospective blinded cohort analysis of clinical cerebral and cochlear fluid pressure (CCFP) device data points obtained in approximately 60 patients; evaluate its potential as a surrogate measure to the clinical gold standard (LP).
2. Determine the age-dependent distribution of cochlear aqueduct patency in this patient population.

Resources (None Listed)

Deliverables (1)

Category: Technology or Tool
Subcategory: Informatics

Description:
A final report detailing the correlation between CCFP readings and LP measurements in the clinical population as well as the age-dependent cochlear aqueduct patency was delivered in May, 2014.

Internal Customers:
Human Health Countermeasures
External Customers:
None

Mappings

Risk of Spaceflight Associated Neuro-ocular Syndrome (SANS)

SANS-301: Develop and test mechanical countermeasures in the laboratory.

Related Tasks (99)

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Risk Approach Plans (1)

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Common Item(s)
	Risk of Spaceflight Associated Neuro-ocular Syndrome (SANS)