HRR - Task - Modulation of Muscle Function by Lower Limb Loading during Space Flight

Evidence Risks Gaps Tasks Reports

Explore Search

- M24
  - Muscle

Modulation of Muscle Function by Lower Limb Loading during Space Flight (Completed)

Last Published: 11/23/20 11:55:12 AM (Central)

Task Book: Entry
Principal Investigator: Laughlin, Mitzi

Short Title: Lower Limb Modulation

Responsible HRP Element: Human Health Countermeasures

Collaborating Org(s):

Funding Status: Completed - Task completed and produced a deliverable

Procurement Mechanism(s):

Solicited

Aims:

Develop protocol to study astronaut volunteers before flight and on multiple occasions during flight using the MARES device to provide loading to the feet and legs as well as device that can apply pressure to the soles of the feet. The effects on muscle activation and performance associated with foot pressure alone or foot pressure plus lower limb loading will be investigated.

Integration/Unique Aspects: This entry reflects only definition phase of the grant

Resources (None Listed)

Deliverables (0)

Mappings

Risk of Impaired Performance Due to Reduced Muscle Mass, Strength & Endurance

M24: Characterize the time course of changes in muscle protein turnover, muscle mass, and function during long duration space flight.

Modulation of Muscle Function by Lower Limb Loading during Space Flight

Related Tasks (65)

Standardized “Pre-flight” Exercise Tests to Predict Performance during Extravehicular Activities in a Lunar Environment

Common Item(s)
	Risk of Impaired Performance Due to Reduced Muscle Mass, Strength & Endurance

Integrated Resistance and Aerobic Training Study (Ploutz-Snyder)

Common Item(s)
	Risk of Impaired Performance Due to Reduced Muscle Mass, Strength & Endurance

Testosterone Supplementation as a Countermeasure against Musculoskeletal Losses during Space Exploration

Common Item(s)
	Risk of Impaired Performance Due to Reduced Muscle Mass, Strength & Endurance

Biomechanical Analysis of Treadmill Locomotion on the International Space Station

Common Item(s)
	Risk of Impaired Performance Due to Reduced Muscle Mass, Strength & Endurance

Integrated Endurance and Resistance Exercise Countermeasures Using a Gravity Independent Training Device

Common Item(s)
	Risk of Impaired Performance Due to Reduced Muscle Mass, Strength & Endurance

Ground-based Biomechanical Analyses of Resistance Exercise Using the Advanced Resistive Exercise Device

Common Item(s)
	Risk of Impaired Performance Due to Reduced Muscle Mass, Strength & Endurance

Common Item(s)
	Risk of Impaired Performance Due to Reduced Muscle Mass, Strength & Endurance

A New Harness For Use with Exercise Countermeasures-Validation of Improved Comfort and Loading with the Center for Space Medicine (CSM) Harness

Common Item(s)
	Risk of Impaired Performance Due to Reduced Muscle Mass, Strength & Endurance

Common Item(s)
	Risk of Impaired Performance Due to Reduced Muscle Mass, Strength & Endurance

Common Item(s)
	Risk of Impaired Performance Due to Reduced Muscle Mass, Strength & Endurance
	M24: Characterize the time course of changes in muscle protein turnover, muscle mass, and function during long duration space flight.

Reliability of the Power Cycle: A Comparsion to Current NASA Exercise Laboratory Muscle Performance Tests

Common Item(s)
	Risk of Impaired Performance Due to Reduced Muscle Mass, Strength & Endurance

Enhancing the Efficacy of Musculoskeletal Countermeasures Using Computer Simulation

Common Item(s)
	Risk of Impaired Performance Due to Reduced Muscle Mass, Strength & Endurance

Assessment of the Time Courses of Leg Muscle Strength and Performance Losses During Prolonged Spaceflight using MARES (Laughlin)

Common Item(s)
	Risk of Impaired Performance Due to Reduced Muscle Mass, Strength & Endurance
	M24: Characterize the time course of changes in muscle protein turnover, muscle mass, and function during long duration space flight.

Space Suit Simulator (S3) for Partial Gravity EVA Experimentation and Testing

Common Item(s)
	Risk of Impaired Performance Due to Reduced Muscle Mass, Strength & Endurance

ESPRIT: Exercise Sensing and Pose Recovery Inference Tool

Common Item(s)
	Risk of Impaired Performance Due to Reduced Muscle Mass, Strength & Endurance

Redox Modulation of Skeletal Muscle Function in Microgravity

Common Item(s)
	Risk of Impaired Performance Due to Reduced Muscle Mass, Strength & Endurance

The Constant Force Resistive Exercise Unit (CFREU) for Multi-Functional Exercise

Common Item(s)
	Risk of Impaired Performance Due to Reduced Muscle Mass, Strength & Endurance

Integrated Resistance and Aerobic Exercise Training with Small Compact Exercise Equipment

Common Item(s)
	Risk of Impaired Performance Due to Reduced Muscle Mass, Strength & Endurance

Development of a Submaximal Cycling Protocol to Identify the Ventilatory Threshold in Astronauts: Application to Monitor Changes in Endurance Capacity in Response to Long-Duration Spaceflight Missions

Common Item(s)
	Risk of Impaired Performance Due to Reduced Muscle Mass, Strength & Endurance

Compact, Controlled Force Crew Exercise System

Common Item(s)
	Risk of Impaired Performance Due to Reduced Muscle Mass, Strength & Endurance

Controlled Resistance Exercise Device

Common Item(s)
	Risk of Impaired Performance Due to Reduced Muscle Mass, Strength & Endurance

Computer-Controlled Force Generator

Common Item(s)
	Risk of Impaired Performance Due to Reduced Muscle Mass, Strength & Endurance

ON HOLD: Biomechanical Analyses of Resistance Exercise Using the Advanced Resistive Exercise Device (Ferrigno)

Common Item(s)
	Risk of Impaired Performance Due to Reduced Muscle Mass, Strength & Endurance

In-flight Demonstration of Portable Load Monitoring Devices-Phase I: XSENS ForceShoe™

Common Item(s)
	Risk of Impaired Performance Due to Reduced Muscle Mass, Strength & Endurance

Retrospective analysis of inflight exercise loading and health outcomes

Common Item(s)
	Risk of Impaired Performance Due to Reduced Muscle Mass, Strength & Endurance

Identification of skeletal muscle performance thresholds for extended duration functional task performance.

Common Item(s)
	Risk of Impaired Performance Due to Reduced Muscle Mass, Strength & Endurance

Common Item(s)
	Risk of Impaired Performance Due to Reduced Muscle Mass, Strength & Endurance

Common Item(s)
	Risk of Impaired Performance Due to Reduced Muscle Mass, Strength & Endurance

Common Item(s)
	Risk of Impaired Performance Due to Reduced Muscle Mass, Strength & Endurance

Common Item(s)
	Risk of Impaired Performance Due to Reduced Muscle Mass, Strength & Endurance

Common Item(s)
	Risk of Impaired Performance Due to Reduced Muscle Mass, Strength & Endurance

Common Item(s)
	Risk of Impaired Performance Due to Reduced Muscle Mass, Strength & Endurance

Evaluation of Advanced Exercise Concepts Devices for Down-Select Decision (Perusek)

Common Item(s)
	Risk of Impaired Performance Due to Reduced Muscle Mass, Strength & Endurance

Common Item(s)
	Risk of Impaired Performance Due to Reduced Muscle Mass, Strength & Endurance

Common Item(s)
	Risk of Impaired Performance Due to Reduced Muscle Mass, Strength & Endurance

Common Item(s)
	Risk of Impaired Performance Due to Reduced Muscle Mass, Strength & Endurance

Common Item(s)
	Risk of Impaired Performance Due to Reduced Muscle Mass, Strength & Endurance

Common Item(s)
	Risk of Impaired Performance Due to Reduced Muscle Mass, Strength & Endurance

Common Item(s)
	Risk of Impaired Performance Due to Reduced Muscle Mass, Strength & Endurance

Common Item(s)
	Risk of Impaired Performance Due to Reduced Muscle Mass, Strength & Endurance

Common Item(s)
	Risk of Impaired Performance Due to Reduced Muscle Mass, Strength & Endurance

Common Item(s)
	Risk of Impaired Performance Due to Reduced Muscle Mass, Strength & Endurance

Common Item(s)
	Risk of Impaired Performance Due to Reduced Muscle Mass, Strength & Endurance

Common Item(s)
	Risk of Impaired Performance Due to Reduced Muscle Mass, Strength & Endurance

Common Item(s)
	Risk of Impaired Performance Due to Reduced Muscle Mass, Strength & Endurance
	M24: Characterize the time course of changes in muscle protein turnover, muscle mass, and function during long duration space flight.

Common Item(s)
	Risk of Impaired Performance Due to Reduced Muscle Mass, Strength & Endurance
	M24: Characterize the time course of changes in muscle protein turnover, muscle mass, and function during long duration space flight.

Exploring the Relationship between In-Flight Training Load Data and Musculoskeletal Health Outcomes

Common Item(s)
	Risk of Impaired Performance Due to Reduced Muscle Mass, Strength & Endurance

EVA Health and Human Performance Benchmarking Study

Common Item(s)
	Risk of Impaired Performance Due to Reduced Muscle Mass, Strength & Endurance

Identification of Muscle Fitness Standards For Exploration Mission Tasks

Common Item(s)
	Risk of Impaired Performance Due to Reduced Muscle Mass, Strength & Endurance

Common Item(s)
	Risk of Impaired Performance Due to Reduced Muscle Mass, Strength & Endurance

Common Item(s)
	Risk of Impaired Performance Due to Reduced Muscle Mass, Strength & Endurance

Common Item(s)
	Risk of Impaired Performance Due to Reduced Muscle Mass, Strength & Endurance

Common Item(s)
	Risk of Impaired Performance Due to Reduced Muscle Mass, Strength & Endurance
	M24: Characterize the time course of changes in muscle protein turnover, muscle mass, and function during long duration space flight.

Omics and biochemical markers of cardiovascular and bone health: Relationship with bedrest and standard physiological measures

Common Item(s)
	Risk of Impaired Performance Due to Reduced Muscle Mass, Strength & Endurance

Identification of functional metabolomic alterations during the simulated spaceflight environment. (Rana)

Common Item(s)
	Risk of Impaired Performance Due to Reduced Muscle Mass, Strength & Endurance

Identification of Functional Metabolomic Profiles Contributing to Physiological Adaptations to Simulated Spaceflight. (Rana)

Common Item(s)
	Risk of Impaired Performance Due to Reduced Muscle Mass, Strength & Endurance

Gravitational dose and multi-system physiologic response

Common Item(s)
	Risk of Impaired Performance Due to Reduced Muscle Mass, Strength & Endurance

Common Item(s)
	Risk of Impaired Performance Due to Reduced Muscle Mass, Strength & Endurance

Musculoskeletal response to a partial-gravity analog in rats: structural, functional and molecular alterations (Rutkove)

Common Item(s)
	Risk of Impaired Performance Due to Reduced Muscle Mass, Strength & Endurance
	M24: Characterize the time course of changes in muscle protein turnover, muscle mass, and function during long duration space flight.

Development of a Muscle Adaptation in Space-flight Simulator ("MASS")

Common Item(s)
	Risk of Impaired Performance Due to Reduced Muscle Mass, Strength & Endurance
	M24: Characterize the time course of changes in muscle protein turnover, muscle mass, and function during long duration space flight.

Common Item(s)
	Risk of Impaired Performance Due to Reduced Muscle Mass, Strength & Endurance

Common Item(s)
	Risk of Impaired Performance Due to Reduced Muscle Mass, Strength & Endurance

Temporal changes in astronauts muscle and cardiorespiratory physiology pre, during, and post spaceflight (Downs)

Common Item(s)
	Risk of Impaired Performance Due to Reduced Muscle Mass, Strength & Endurance

Dose-Response Study of Musculoskeletal Outcomes Following Centrifugation in Adult Mice on ISS (Bouxsein)

Common Item(s)
	Risk of Impaired Performance Due to Reduced Muscle Mass, Strength & Endurance

Time Course of Spaceflight-Induced Adaptations in Bone Morphology, Bone Strength and Muscle Quality (Bouxsein)

Common Item(s)
	Risk of Impaired Performance Due to Reduced Muscle Mass, Strength & Endurance
	M24: Characterize the time course of changes in muscle protein turnover, muscle mass, and function during long duration space flight.

Print View...

PRRs (1)

This task can be found in the following Paths to Risk Reduction.

Muscle Path to Risk Reduction