Last Published:  11/23/20 11:55:12 AM (Central)
Short Title: HZE Gliomagenesis-2
Responsible HRP Element: Space Radiation
Collaborating Org(s):
Funding Status: Completed - Task completed and produced a deliverable
Procurement Mechanism(s):
Solicited
Aims:
In this proposal, we aim to use further finessed versions of our current mouse models to analyze not only the tumorigenic potential of an array of particles and doses, but also to identify the cell types in the brain that are most susceptible to transformation following charged particle exposure. Furthermore, we propose to undertake large scale oncogenomic studies to identify pathways that are altered in particle-induced GBMs.
Resources (None Listed)
Mappings
RiskRisk of Acute (In-flight) and Late Central Nervous System Effects from Radiation Exposure
You are here!TaskMouse Glioma Models to Estimate Cancer Risks from HZE Particle Exposure

RiskRisk of Cardiovascular Disease and Other Degenerative Tissue Effects From Radiation Exposure and Secondary Spaceflight Stressors
You are here!TaskMouse Glioma Models to Estimate Cancer Risks from HZE Particle Exposure

RiskRisk of Radiation Carcinogenesis
You are here!TaskMouse Glioma Models to Estimate Cancer Risks from HZE Particle Exposure