Task Characterization of Psychological Risk, Overlap with Physical Health, and Associated Performance in Isolated, Confined, Extreme (ICE) Environments
Last Published:  07/30/20 02:45:15 PM (Central)
Short Title: Neurobehavioral Conditions List
Responsible HRP Element: Human Factors and Behavioral Performance
Collaborating Org(s):
Funding Status: Active - Currently funded and in progress
Procurement Mechanism(s):
This task aims to develop and validate a measure (i.e., checklist) through which flight surgeons can systematically evaluate symptoms of adverse neurobehavioral conditions that may occur over long-duration exploration missions.

Aim 1: To summarize available evidence of psychological and behavioral symptoms experienced in isolated, confined, extreme (ICE) environments and exploration spaceflight based on comprehensive literature reviews and interviews with subject matter experts.

Aim 2: To define and compare the prevalence, severity, and duration of discrete psychological/behavioral symptoms experienced among HERA and Antarctic winterover cohorts, including concurrent and sequential overlap with physical health symptoms.


Aim 3: To explore relationships among cognitive/perception performance, sleep patterns and biomarkers of stress with psychological and behavioral symptoms in ICE environments.


RiskRisk of Adverse Cognitive or Behavioral Conditions and Psychiatric Disorders
GapBMed-101: We need to identify, quantify, and validate the key selection factors for astronaut cognitive and behavioral strengths (e.g., resiliency) and operationally-relevant performance threats for increasingly Earth independent, long-duration, autonomous, and/or long-distance exploration missions.
GapBMed-102: Given exposures to spaceflight hazards (space radiation, isolation), how do we identify individual susceptibility, monitor molecular/biomarkers and acceptable thresholds, and validate behavioral health and CNS/neurological/neuropsychological performance measures and domains of relevance to exploration class missions?
GapBMed-103: What are the validated, efficacious treatments (individual or Team-based) and/or countermeasures to prevent adverse behavioral conditions, CNS/neurological, and/or psychiatric disorders caused by either single and/or integrated exposures to spaceflight hazards during exploration class missions?
GapBMed-108: Given each crewmember will experience multiple spaceflight hazards simultaneously, we need to identify and characterize the potential additive, antagonistic, or synergistic impacts of multiple stressors (e.g., space radiation, altered gravity, isolation, altered immune, altered sleep) on crew health and/or CNS/ cognitive functioning to develop threshold limits and validate countermeasures for any identified adverse crew health and/or operationally-relevant performance outcomes.
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