Funding Status:
Completed - Task completed and produced a deliverable
Procurement Mechanism(s):
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Aims:
Aim 1: Determine structural and gene expression changes in cortical and cancellous bone in
growing rats (3 month old) during long-duration simulated microgravity exposure and recovery.
Aim 2: Determine whether skeletal responses to long-duration simulated microgravity differ
in males compared to females (3 month old).
Aim 3: Determine age effects (9 mo old) on temporal changes in skeletal structure and gene
expression during extended simulated microgravity followed by recovery.