Task Combined Effects of Space Radiation and Microgravity on the Function of Human Capillaries and the Endothelial Barrier: Implications for Degenerative Disorders
Last Published:  07/30/20 02:45:15 PM (Central)
Short Title: Implications for Degenerative Disorders
Responsible HRP Element: Human Health Countermeasures
Collaborating Org(s):
Funding Status: Active - Currently funded and in progress
Procurement Mechanism(s):
Solicited
Aims:

Specific aim 1 endothelial barrier function.

To determine the permeability and tight junction integrity of experimental models

exposed to high and low LET space radiation in conjunction with microgravity.

Specific aim 2 Angiogenesis and mature vessel integrity.

To determine the additive or synergistic effect of microgravity on the effect of space

radiation on angiogenesis and on mature vessels.


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RiskRisk of Adverse Health Event Due to Altered Immune Response
You are here!TaskCombined Effects of Space Radiation and Microgravity on the Function of Human Capillaries and the Endothelial Barrier: Implications for Degenerative Disorders

RiskRisk of Spaceflight Induced Cardiovascular Disease
You are here!TaskCombined Effects of Space Radiation and Microgravity on the Function of Human Capillaries and the Endothelial Barrier: Implications for Degenerative Disorders