Task Molecular characterization of transmissible chromosome aberrations produced by ions of intermediate and high atomic number
Last Published:  03/26/21 03:34:00 PM (Central)
Short Title: Chromosome Aberrations
Responsible HRP Element: Space Radiation
Collaborating Org(s):
Funding Status: Active - Currently funded and in progress
Procurement Mechanism(s):

Objective 1: Isolate progeny (clones) of irradiated single cells and analyze for the presence of transmissible chromosome aberrations

Objective 2:
Next generation sequencing approaches will be employed to characterize, at the DNA level, the nature of breakpoint junctions of the chromosome translocations and inversions identified in Objective 1.

Objective 3: Examine cytogenetic Effects of Abrogating CtIP activity.
Resources (None Listed)